Anaspec/West Nile Virus NS3 Protease, recombinant/5 µg/AS-72081-5
商品编号:
AS-72081-5
品牌:
Anaspec
市场价:
¥1620.00
美元价:
810.00
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
Product Name | West Nile Virus NS3 Protease, recombinant |
Size | 5 µg |
Catalog # | AS-72081-5 |
US$ | $81 |
The West Nile Virus (WNV) NS3 protease is absolutely essential (along with viral-encoded cofactor NS2B) for post-translational processing of a viral polypeptide precursor in infected host cells. This polypeptide provides the structural and functional viral proteins, and inhibition of its processing could represent a potential treatment for viral infections. Thus, this protease has become one of the key targets for developing anti-WNV drugs. Recombinant WNV NS3 protease can be used in enzyme assay with SensoLyte 440, or 570 WNV protease Assay Kits (Cat#72079, 72080) for screening of WNV NS3 inhibitors. | |
Detailed Information | DatasheetMaterial Safety Data Sheets (MSDS) |
Storage | -80 °C |
品牌介绍
Anaspec阳离子抗菌肽是所有物种先天防御的重要组成部分。在许多生物中,包括真菌,昆虫,两栖动物和人类中,已经鉴定出100多种这些肽。这些疏水性和两亲性肽表现出抗生素,杀真菌,溶血,杀病毒和杀肿瘤活性。基于它们的结构特性,这些抗菌肽可分为三类:螺旋状肽,含有一个至几个二硫键的肽以及富含某些氨基酸(例如脯氨酸或色氨酸)的肽。这些肽大多数具有一些共同的特征,例如它们的低分子量(2-5 kDa),存在多个赖氨酸和精氨酸残基以及两亲性质。尽管尚不清楚它们杀死细菌的确切机制,但已表明导致膜渗透的肽-脂相互作用在其活性中起作用。抗生素肽的实例包括洋甘菊素,其由皮肤的皮肤分泌。非洲爪蟾 ; 人嗜中性粒细胞的防御素和人唾液中的组蛋白。天蚕素是由昆虫在感染条件下产生的。天蚕素A,B和D是紧密的同源物,由天蚕素蛾的35中发现的35-39个残基组成。
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