Anaspec/SensoLyte®；490 HCV蛋白酶检测试剂盒*荧光法*/1试剂盒/AS-72087
市场价：
¥9600.00
美元价：
4800.00
产品分类：
人体抗原
公司分类：
human_antigen
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| Product Name | SensoLyte ® 490 HCV Protease Assay Kit *Fluorimetric*Kit Size: 200 assays |
| Size | 1 kit |
| Catalog # | AS-72087 |
| US$ | $480 |
HCV protease is identified as an important drug-screening target. The SensoLyte® 490 HCV Protease Assay Kit uses an optimized FRET peptide substrate for the continuous measurement of HCV NS3/4a activity. This FRET substrate is cleaved specifically by HCV NS3/4a protease thereby liberating the C-terminal peptide-fluorophore fragment from the proximity quenching effect of the dark quencher, resulting in a more than 10-fold increase in fluorescence. This assay can detect HCV NS3/4a protease activity at 1 pmole. The kit contains: EDANS/DABCYL-based FRET peptide substrate (Ex/Em=340/490 nm upon cleavage) Assay buffer Fluorescence reference standard for calibration A detailed protocol | |
| Detailed Information |  Datasheet Material Safety Data Sheets (MSDS) |
| Product Citations | Park, HR. et al. (2011). 2-arylmethylaminomethyl-5,6-dihydroxychromone derivatives with selective anti-HCV activity. Bioorg Med Chem Lett 10.1016/j.bmcl.2011.04.055.Peng, LF. et al. (2011). Ceestatin, a novel small molecule inhibitor of hepatitis C virus replication, inhibits 3-hydroxy-3-methylglutaryl-coenzyme A synthase. J Infect Dis 204, 609.Frick, DN. et al. (2010). A method to simultaneously monitor hepatitis C virus NS3 helicase and protease activities. Methods Mol Biol 587, 223. |
品牌介绍
Anaspec阳离子抗菌肽是所有物种先天防御的重要组成部分。在许多生物中，包括真菌，昆虫，两栖动物和人类中，已经鉴定出100多种这些肽。这些疏水性和两亲性肽表现出抗生素，杀真菌，溶血，杀病毒和杀肿瘤活性。基于它们的结构特性，这些抗菌肽可分为三类：螺旋状肽，含有一个至几个二硫键的肽以及富含某些氨基酸（例如脯氨酸或色氨酸）的肽。这些肽大多数具有一些共同的特征，例如它们的低分子量（2-5 kDa），存在多个赖氨酸和精氨酸残基以及两亲性质。尽管尚不清楚它们杀死细菌的确切机制，但已表明导致膜渗透的肽-脂相互作用在其活性中起作用。抗生素肽的实例包括洋甘菊素，其由皮肤的皮肤分泌。非洲爪蟾 ; 人嗜中性粒细胞的防御素和人唾液中的组蛋白。天蚕素是由昆虫在感染条件下产生的。天蚕素A，B和D是紧密的同源物，由天蚕素蛾的35中发现的35-39个残基组成。
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