Anaspec/人MMP-1，原酶/100 uL/AS-72004
市场价：
¥1960.00
美元价：
980.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| Product Name | Human MMP - 1, Proenzyme100 uL, 10ug/mL |
| Size | 100 uL |
| Catalog # | AS-72004 |
| US$ | $98 |
Matrix metalloproteinases (MMPs) belong to a family of secreted or membrane-associated zinc endopeptidases capable of digesting extracellular matrix components. The human MMP-1 is purified from fibroblasts and becomes highly active when incubated with APMA. It can be used as a positive control in FRET-based enzyme activity assay, zymography, Western blot, IP, and ELISA. This is sold as a pro-form and activation is required. | |
| Detailed Information |  Datasheet Material Safety Data Sheets (MSDS) |
| Product Citations | Bahney, C. et al. (2011). A bioresponsive hydrogel tuned to chondrogenesis of human mesenchymal stem cells. FASEB J doi: 10.1096/fj.10-165514.Salsas-Escat, R. et al. (2010). Cleavage Site Specificity and Conformational Selection in Type I Collagen Degradation. Biochem 49, 4147.Spiga, M. et al. (2010). Development of a Gene Therapy Virus with a Glucocorticoid-Inducible MMP1 for the Treatment of Steroid Glaucoma. Investigat Ophthalmol Visual Sci 51, 3029. |
品牌介绍
Anaspec阳离子抗菌肽是所有物种先天防御的重要组成部分。在许多生物中，包括真菌，昆虫，两栖动物和人类中，已经鉴定出100多种这些肽。这些疏水性和两亲性肽表现出抗生素，杀真菌，溶血，杀病毒和杀肿瘤活性。基于它们的结构特性，这些抗菌肽可分为三类：螺旋状肽，含有一个至几个二硫键的肽以及富含某些氨基酸（例如脯氨酸或色氨酸）的肽。这些肽大多数具有一些共同的特征，例如它们的低分子量（2-5 kDa），存在多个赖氨酸和精氨酸残基以及两亲性质。尽管尚不清楚它们杀死细菌的确切机制，但已表明导致膜渗透的肽-脂相互作用在其活性中起作用。抗生素肽的实例包括洋甘菊素，其由皮肤的皮肤分泌。非洲爪蟾 ; 人嗜中性粒细胞的防御素和人唾液中的组蛋白。天蚕素是由昆虫在感染条件下产生的。天蚕素A，B和D是紧密的同源物，由天蚕素蛾的35中发现的35-39个残基组成。
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