Anaspec/SensoLyte和174；520 MMP基质取样器试剂盒*荧光法*/1试剂盒/AS-71170
市场价：
¥13960.00
美元价：
6980.00
产品分类：
抗小鼠
公司分类：
Anti_mouse
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| Product Name | SensoLyte ® 520 MMP Substrate Sampler Kit *Fluorimetric* |
| Size | 1 kit |
| Catalog # | AS-71170 |
| US$ | $698 |
Matrix metalloproteinases (MMPs) belong to a family of secreted or membrane-associated proteins capable of digesting extracellular matrix components. They are involved in diseases such as cancer, arthritis, asthma, angiogenesis, alopecia and metastasis. They are also identified as drug-screening targets. SensoLyte® 520 MMP Substrate Sampler Kit contains a series of FRET peptide substrates for use as fluorogenic indicators to assay MMP protease activities. It provides the best solution for identifying a suitable fluorogenic substrate for a particular MMP assay. All the MMP substrates in the kit are also available in bulk packages. Kit size: 16X 20 assays | |
| Detailed Information |  Datasheet Material Safety Data Sheets (MSDS) |
| Storage | -20°C |
| Product Citations | Wirsching, H-G. et al. (2014). Thymosin beta 4 Gene Silencing Decreases Stemness and Invasiveness in Glioblastoma. Brain 137, 433. doi: 10.1093/brain/awt333.Iwakura, Y. et al. (2011). Dopamine-dependent ectodomain shedding and release of epidermal growth factor in developing straitum: target-derived neurotrophic signaling (Part 2). J Neurochem 10.1111/j.1471-4159.2011.07295.x.Allington, TM. et al. (2009). Activated Abl kinase inhibits oncogenic transforming growth factor-β signaling and tumorigenesis in mammary tumors. FASEB J 23, 4231.Schaal, R. et al. (2007). Systematic identification of substrates for profiling of secreted proteases from Aspergillus species. J Microbio Meth 71, 93.White, AR. et al. (2006). Degradation of the Alzheimer Disease amyloid β-peptide by metal-dependent upregulation of metalloprotease activity. J Biol Chem 281, 17670. |
品牌介绍
Anaspec阳离子抗菌肽是所有物种先天防御的重要组成部分。在许多生物中，包括真菌，昆虫，两栖动物和人类中，已经鉴定出100多种这些肽。这些疏水性和两亲性肽表现出抗生素，杀真菌，溶血，杀病毒和杀肿瘤活性。基于它们的结构特性，这些抗菌肽可分为三类：螺旋状肽，含有一个至几个二硫键的肽以及富含某些氨基酸（例如脯氨酸或色氨酸）的肽。这些肽大多数具有一些共同的特征，例如它们的低分子量（2-5 kDa），存在多个赖氨酸和精氨酸残基以及两亲性质。尽管尚不清楚它们杀死细菌的确切机制，但已表明导致膜渗透的肽-脂相互作用在其活性中起作用。抗生素肽的实例包括洋甘菊素，其由皮肤的皮肤分泌。非洲爪蟾 ; 人嗜中性粒细胞的防御素和人唾液中的组蛋白。天蚕素是由昆虫在感染条件下产生的。天蚕素A，B和D是紧密的同源物，由天蚕素蛾的35中发现的35-39个残基组成。
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