| Product Name | SensoLyte ® Generic MMP Assay Kit Colorimetric |
| Size | 1 kit |
| Catalog # | AS-72095 |
| US$ | $380 |
Matrix metalloproteinases (MMPs) belong to a family of secreted or membrane-associated proteins capable of digesting extracellular matrix components. The importance of MMPs in tumor development and invasion as well as other diseases is well known. The SensoLyte® Generic MMP Assay Kit can be used to detect the activity of a variety of MMPs, including MMP-1, 2, 3, 7, 8, 9, 12, 13, and 14 or for high throughput screening of MMPs inducers and inhibitors. The substrate is a thiopeptolide that is cleaved by the MMPs, releasing a sulfhydryl group, which can be detected with a color-developing thiol-reactive agent, 4,4-dithiodipyridine or Ellmans Reagent at 412 nm using a microplate reader. The assays are performed in a convenient 96-well microplate format. Kit size: 100 assays | |
| Detailed Information |  Datasheet Material Safety Data Sheets (MSDS) |
| Storage | -20°C |
| Product Citations | Tezvergil-Mutluay, A. et al. (2012). Carbodiimide cross-linking inactivates soluble and matrix-bound MMPs, in vitro JDR 91, 192-196.Thompson, J. et al. (2012). Inhibition of endogenous dentin matrix metalloproteinases by ethylenediaminetetraacetic acid. JOE,38, 62.Tezvergil-Mutluay, A. et al. (2011). The Inhibitory Effects of Quaternary Ammonium Methacrylates on Soluble and Matrix-bound MMPs. JDR doi: 10.1177/0022034510389472.Tezvergil, A. et al. (2010). The inhibitory effect of polyvinylphosphonic acid on functional MMP activities in human demineralized dentin. Acta Biomaterialia doi:10.1016/j.actbio.2010.05.017. |
