| Product Name | SensoLyte ® 440 Cathepsin S Assay Kit *Fluorimetric* |
| Size | 1 kit |
| Catalog # | AS-72100 |
| US$ | $434 |
Cathepsins are a class of globular lysosomal proteases playing a vital role in mammalian cellular turnover. They degrade polypeptides and are distinguished by their substrate specificities. Cathepsin S is a cysteine proteinase involved in the pathogenesis of autoimmune diseases, atherosclerosis, cancer, obesity and related diseases.The SensoLyte® 440 Cathepsin S Assay Kit uses a fluorogenic peptide for measurement of enzyme activity. This peptide releases the AMC (7-amino-4-methylcoumarin) fluorophore upon cathepsin S cleavage, and which can be detected with excitation at 354 nm and emission at 442 nm.The kit contains: AMC based fluorogenic substrate (Ex/Em=354 nm/442 nm upon cleavage) Assay buffer Human spleen Cathepsin S Inhibitor Fluorescence reference standard for calibration A detailed protocol Kit size: 100 assays (96-well plate) | |
| Detailed Information |  Datasheet Material Safety Data Sheets (MSDS) |
| Storage | -20°C |
