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当前位置: 首页 > 产品中心 > Standards > Anaspec/SensoLyte和174;抗MOG(35-55)IgG定量ELISA试剂盒(小鼠/大鼠)/1试剂盒/AS-54465
商品详细Anaspec/SensoLyte和174;抗MOG(35-55)IgG定量ELISA试剂盒(小鼠/大鼠)/1试剂盒/AS-54465
Anaspec/SensoLyte和174;抗MOG(35-55)IgG定量ELISA试剂盒(小鼠/大鼠)/1试剂盒/AS-54465
Anaspec/SensoLyte和174;抗MOG(35-55)IgG定量ELISA试剂盒(小鼠/大鼠)/1试剂盒/AS-54465
商品编号: AS-54465
品牌: Anaspec
市场价: ¥9600.00
美元价: 4800.00
产地: 美国(厂家直采)
公司:
产品分类: 标准品
公司分类: Standards
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
Description
Product NameSensoLyte ® Anti - MOG(35 - 55) IgG Quantitative ELISA Kit (mouse/rat)
Size1 kit
Catalog #AS-54465
US$$480

MOG peptide fragment (35-55) [Cat# 60130] induces autoantibody production and relapsing-remitting neurological disease causing extensive plaque-like demyelination. Autoantibody response to MOG (35-55) is present in multiple sclerosis (MS) patients and MOG (35-55)-induced experimental autoimmune encephalomyelitis (EAE) mice. The SensoLyte® Anti-MOG (35-55) IgG Quantitative ELISA Kit (mouse/rat) provides a convenient, quantitative assay for detecting anti-MOG (35-55) IgG. This colorimetric assay, useful for determining the amount of anti-MOG (35-55) IgG present, can help provide information on the role anti-MOG (35-55) IgG plays in the development of EAE, an in vivo animal model for MS pathogenesis.The assays are performed in a convenient 96-well (strips format). The kit contains: • Pre-coated and pre-blocked 96-well strip plate• Standard for calibration • A detailed protocol Kit Size: 96 assays

Detailed InformationDatasheet
Material Safety Data Sheets (MSDS)
Storage4°C
Product CitationsDoran, T. et al. (2015). High affinity binding of conformationally constrained synthetic oligomers to an antigen-specific antibody: Discovery of a diagnostically useful synthetic ligand for murine Type 1 diabetes autoantibodies. J.bmcl 25, 21, 4910-4917.https://doi.org/10.1016/j.bmcl.2015.05.046Hatterer, E. et al. (2008). Cerebrospinal fluid dendritic cells infiltrate the brain parenchyma and target the cervical lymph nodes under neuroinflammatory conditions. PLoS ONE 3, e3321.
品牌介绍
Anaspec阳离子抗菌肽是所有物种先天防御的重要组成部分。在许多生物中,包括真菌,昆虫,两栖动物和人类中,已经鉴定出100多种这些肽。这些疏水性和两亲性肽表现出抗生素,杀真菌,溶血,杀病毒和杀肿瘤活性。基于它们的结构特性,这些抗菌肽可分为三类:螺旋状肽,含有一个至几个二硫键的肽以及富含某些氨基酸(例如脯氨酸或色氨酸)的肽。这些肽大多数具有一些共同的特征,例如它们的低分子量(2-5 kDa),存在多个赖氨酸和精氨酸残基以及两亲性质。尽管尚不清楚它们杀死细菌的确切机制,但已表明导致膜渗透的肽-脂相互作用在其活性中起作用。抗生素肽的实例包括洋甘菊素,其由皮肤的皮肤分泌。非洲爪蟾 ; 人嗜中性粒细胞的防御素和人唾液中的组蛋白。天蚕素是由昆虫在感染条件下产生的。天蚕素A,B和D是紧密的同源物,由天蚕素蛾的35中发现的35-39个残基组成。