Anaspec/攻击ᵀᴹ β - 淀粉样蛋白(1-40),人/0.25毫克净肽/AS-72215
市场价:
¥5420.00
美元价:
2710.00
产品分类:
逆转录试剂盒
公司分类:
Sensiscript_RT_Kit
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
Product Name | AggreSureᵀᴹβ - Amyloid (1 - 40), humanDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVV |
Size | 0.25 mg NET peptide |
Catalog # | AS-72215 |
US$ | $271 |
Purity | >95% |
AggreSure beta-Amyloid (1-40) peptide is pretreated and tested for aggregation using SensoLyte® ThT Aβ40 Aggregation kit (Cat# 72213). Aggregation is guaranteed.
| |
Detailed Information | DatasheetMaterial Safety Data Sheets (MSDS) |
Storage | 20°C |
Molecular Weight | 4329.9 |
DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVV | |
Sequence(Three-Letter Code) | H - Asp - Ala - Glu - Phe - Arg - His - Asp - Ser - Gly - Tyr - Glu - Val - His - His - Gln - Lys - Leu - Val - Phe - Phe - Ala - Glu - Asp - Val - Gly - Ser - Asn - Lys - Gly - Ala - Ile - Ile - Gly - Leu - Met - Val - Gly - Gly - Val - Val - OH |
Product Citations | Maneshi, MM. et al. (2018). Enantiomeric Aβ peptides inhibit the fluid shear stress response of PIEZO1. Sci Rep 8(1):14267. doi: 10.1038/s41598-018-32572-2.Hartz. AM, et al. (2016). Aβ40 Reduces P-Glycoprotein at the Blood-Brain Barrier through the Ubiquitin-Proteasome Pathway. J Neurosci. 36(6):1930-41. doi:10.1523/JNEUROSCI.0350-15.2016.Debner EK & King JM. (2016). Effects of Melatonin and Beta-Amyloid on Mitochondrial Function in a Model of Aging Mouse Astrocytes. The FASEB J 30(1_supplement):702-1. |
品牌介绍
Anaspec阳离子抗菌肽是所有物种先天防御的重要组成部分。在许多生物中,包括真菌,昆虫,两栖动物和人类中,已经鉴定出100多种这些肽。这些疏水性和两亲性肽表现出抗生素,杀真菌,溶血,杀病毒和杀肿瘤活性。基于它们的结构特性,这些抗菌肽可分为三类:螺旋状肽,含有一个至几个二硫键的肽以及富含某些氨基酸(例如脯氨酸或色氨酸)的肽。这些肽大多数具有一些共同的特征,例如它们的低分子量(2-5 kDa),存在多个赖氨酸和精氨酸残基以及两亲性质。尽管尚不清楚它们杀死细菌的确切机制,但已表明导致膜渗透的肽-脂相互作用在其活性中起作用。抗生素肽的实例包括洋甘菊素,其由皮肤的皮肤分泌。非洲爪蟾 ; 人嗜中性粒细胞的防御素和人唾液中的组蛋白。天蚕素是由昆虫在感染条件下产生的。天蚕素A,B和D是紧密的同源物,由天蚕素蛾的35中发现的35-39个残基组成。
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