Anaspec/SensoLyte和174；抗α-突触核蛋白（人）ELISA试剂盒/1试剂盒/AS-55550-H
商品编号：
AS-55550-H
品牌：
Anaspec
市场价：
¥10920.00
美元价：
5460.00
产品分类：
ELISA辅助试剂
公司分类：
ELISA_helper_reagent
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| Product Name | SensoLyte ® Anti - alpha - Synuclein (Human) ELISA Kit |
| Size | 1 kit |
| Catalog # | AS-55550-H |
| US$ | $546 |
This kit is optimized to detect human alpha-Synuclein (α-Synuclein) in cell and tissue lysate, and in human body fluids such as cerebrospinal fluid (CSF) and plasma. Wells are pre-coated with anti-α-Synuclein monoclonal antibodies, blocked, and stabilized for long-term storage. The amount of α-Synuclein is quantified using sandwich ELISA: rabbit polyclonal anti-α-Synuclein specific antibodies directly conjugated to horseradish peroxidase (HRP) are used to detect captured α-Synuclein.One Step Convenient Format o Pre-coated and pre-blocked 96-well strip plateo Ready-to-use substrate solution and other assay componentso One step assay (samples and detection antibody are added simultaneously)o 1 hour assay time at room temperature (excluding incubation time)Minimal Sample Size o Requires only 10-20 μl of cell and tissue lysate or body fluidsHigh Sensitivity o Detects 5 pg/ml of α-Synuclein (calculated as three standard deviations from the blank)Broad Dynamic Range o8-500 pg α-Synuclein/ml in the assayed sampleRELATED PRODUCTS: alpha-Synuclein Recombinant Proteins | |
| Detailed Information |  Datasheet Material Safety Data Sheets (MSDS) |
| Storage | 4°C |
| Product Citations | Tanriöver G, et al. (2020) Prominent microglial inclusions in transgenic mouse models of α-synucleinopathy that are distinct from neuronal lesions. Acta neuropathologica communications. 8(1):133. doi: 10.1186/s40478-020-00993-8.Oh SH, et al. (2017). The cleavage effect of mesenchymal stem cell and its derived matrix metalloproteinase-2 on extracellular α-synuclein aggregates in parkinsonian models. Stem cells translational medicine. 2017 6(3):949-61. doi:10.5966/sctm.2016-0111Vivacqua G, et al. (2016). Abnormal Salivary Total and Oligomeric Alpha-Synuclein in Parkinson"s Disease. PLoS One. 11(3):e0151156. doi: 10.1371/journal.pone.0151156.Prusiner, B. S. (2015). Evidence for α-synuclein prions causing multiple system atrophy in humans with parkinsonism pnas 112 doi: 10.1073/pnas.1514475112.Woerman, A. L. (2015). Propagation of prions causing synucleinopathies in cultured cells. PNAS 112 doi: 10.1073/pnas.1513426112.Al-Nimer, MS. et al. (2014). Saliva α-synuclein and a high extinction coefficient protein: A novel approach in assessment biomarkers of Parkinson"s disease. North Am J Med Sci 6, 633. doi: 10.4103/1947-2714.147980.Maia, LF. et al. (2013). Changes in amyloid-β and tau in the cerebrospinal fluid of transgenic mice overexpressing amyloid precursor protein. Sci Transl Med 5, 194re2.Smith, LM. et al. (2012). α-Synuclein and anti-α-synuclein antibodies in Parkinsons disease, atypical Parkinson syndromes, REM sleep behavior disorder, and healthy controls. PloS One 7, e52285. |
品牌介绍
Anaspec阳离子抗菌肽是所有物种先天防御的重要组成部分。在许多生物中，包括真菌，昆虫，两栖动物和人类中，已经鉴定出100多种这些肽。这些疏水性和两亲性肽表现出抗生素，杀真菌，溶血，杀病毒和杀肿瘤活性。基于它们的结构特性，这些抗菌肽可分为三类：螺旋状肽，含有一个至几个二硫键的肽以及富含某些氨基酸（例如脯氨酸或色氨酸）的肽。这些肽大多数具有一些共同的特征，例如它们的低分子量（2-5 kDa），存在多个赖氨酸和精氨酸残基以及两亲性质。尽管尚不清楚它们杀死细菌的确切机制，但已表明导致膜渗透的肽-脂相互作用在其活性中起作用。抗生素肽的实例包括洋甘菊素，其由皮肤的皮肤分泌。非洲爪蟾 ; 人嗜中性粒细胞的防御素和人唾液中的组蛋白。天蚕素是由昆虫在感染条件下产生的。天蚕素A，B和D是紧密的同源物，由天蚕素蛾的35中发现的35-39个残基组成。
联络我们
