Anaspec/四甲基罗丹明-5-马来酰亚胺/5 mg/AS-81446
市场价：
¥5080.00
美元价：
2540.00
产品分类：
超声波清洗机
公司分类：
Ultrasonic_cleaning
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| Product Name | Tetramethylrhodamine - 5 - maleimide |
| Size | 5 mg |
| Catalog # | AS-81446 |
| US$ | $254 |
Maleimides are among the most frequently used reagents for thiol modification.In most proteins, the sites of reactions are at cysteine residues that either are intrinsically present or result from reduction of cystines. Unlike iodoacetamides, maleimides do not react with histidines and methionines under physiological conditions. Tetramethylrhodamine-5-maleimide is widely used for thiol modifications of peptides and proteins.
| |
| Detailed Information |  Material Safety Data Sheets (MSDS) |
| Storage | -20°C desiccated and protected from light |
| References | 1. Graceffa P and Dominguez R (2003).J Biol Chem 278, 34172-80. 2. Tong Y, et al. (2001).J Gen Physiol 117, 103-18. |
| Molecular Weight | 481.499 |
| Molecular Formula | C28H23 N3O5 |
| Spectral Properties | Abs/Em = 540/567 nm |
| Solvent System | DMF or DMSO |
| Product Citations | Iwamoto, M. & S. Oiki (2013). Amphipathic antenna of an inward rectifier K+ channel responds to changes in the inner membrane leaflet. PNAS 110, 749. doi: 10.1073/pnas.1217323110.Srinivasan, S. et al. (2011). L-selectin transmembrane and cytoplasmic domains are monomeric in membranes. Biochim Biophys Acta-Biomembranes doi:10.1016/j.bbamem.2011.02.006.Bakker, A. et al. (2008). Conditional MHC class I ligands and peptide exchange technology for the human MHC gene products HLA-A1, -A3, -A11, and -B7. PNAS 105, 3825. |
品牌介绍
Anaspec阳离子抗菌肽是所有物种先天防御的重要组成部分。在许多生物中，包括真菌，昆虫，两栖动物和人类中，已经鉴定出100多种这些肽。这些疏水性和两亲性肽表现出抗生素，杀真菌，溶血，杀病毒和杀肿瘤活性。基于它们的结构特性，这些抗菌肽可分为三类：螺旋状肽，含有一个至几个二硫键的肽以及富含某些氨基酸（例如脯氨酸或色氨酸）的肽。这些肽大多数具有一些共同的特征，例如它们的低分子量（2-5 kDa），存在多个赖氨酸和精氨酸残基以及两亲性质。尽管尚不清楚它们杀死细菌的确切机制，但已表明导致膜渗透的肽-脂相互作用在其活性中起作用。抗生素肽的实例包括洋甘菊素，其由皮肤的皮肤分泌。非洲爪蟾 ; 人嗜中性粒细胞的防御素和人唾液中的组蛋白。天蚕素是由昆虫在感染条件下产生的。天蚕素A，B和D是紧密的同源物，由天蚕素蛾的35中发现的35-39个残基组成。
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