Anaspec/EDANS，钠盐/0.5 g/AS-23886
市场价：
¥800.00
美元价：
400.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| Product Name | EDANS, sodium salt5 - [(2 - aminoethyl)amino]naphthalene - 1 - sulfonic acid, sodium salt |
| Size | 0.5 g |
| Catalog # | AS-23886 |
| US$ | $40 |
| Purity | >= 95 % |
EDANS is one of the most popular donors for developing FRET-based nucleic acid probes and protease substrates. EDANS is often paired with DABCYL or DABSYL in FRET-based probes. Its fluorescence is environment-sensitive.
| |
| Detailed Information |  Datasheet Material Safety Data Sheets (MSDS) |
| Storage | -20°C desiccated and protected from light |
| References | Ref: Becker BF, et al. (2002). Application of peptides containing the cleavage sequence of pro-TNFalpha in assessing TACE activity of whole cells. Biol. Chem 383, 1821-6; Cottaz S, et al. (2000). A fluorescence-quenched chitopentaose for the study of endo-chitinases and chitobiosidases. Eur J Biochem 267, 5593-600; Beekman B, et al. (1996). Convenient fluorometric assay for matrix metalloproteinase activity and its application in Biol.ogical media. FEBS Lett 390, 221-5; Wang GT, et al. (1993). A continuous fluorescence assay of renin activity. Anal Biochem 210, 351-9. |
| Molecular Weight | 288.3 |
| Molecular Formula | C12H13N2O3SNa |
| Spectral Properties | Abs/Em = 335/493 nm |
| Solvent System | water/DMSO |
| Product Citations | Peti-Peterdi, J. et al. (2004). Real-time imaging of renin release in vitro. Am J Physiol Renal Physiol287, F329. doi: 10.1152/ajprenal.00420.2003. Darrow, A. L.et al. (2003). Virus-based expression systems facilitate rapid target in vivo functionality validation and high-throughput screening. J Biomol Screen8, 65. doi: 10.1177/1087057102239664. Murata, CE. and Goldberg, DE. (2003). Plasmodium falciparum Falcilysin. A Metalloprotease with dual specificity. J. Biol. Chem. 278, 38022. doi: 10.1074/jbc.M306842200. |
品牌介绍
Anaspec阳离子抗菌肽是所有物种先天防御的重要组成部分。在许多生物中，包括真菌，昆虫，两栖动物和人类中，已经鉴定出100多种这些肽。这些疏水性和两亲性肽表现出抗生素，杀真菌，溶血，杀病毒和杀肿瘤活性。基于它们的结构特性，这些抗菌肽可分为三类：螺旋状肽，含有一个至几个二硫键的肽以及富含某些氨基酸（例如脯氨酸或色氨酸）的肽。这些肽大多数具有一些共同的特征，例如它们的低分子量（2-5 kDa），存在多个赖氨酸和精氨酸残基以及两亲性质。尽管尚不清楚它们杀死细菌的确切机制，但已表明导致膜渗透的肽-脂相互作用在其活性中起作用。抗生素肽的实例包括洋甘菊素，其由皮肤的皮肤分泌。非洲爪蟾 ; 人嗜中性粒细胞的防御素和人唾液中的组蛋白。天蚕素是由昆虫在感染条件下产生的。天蚕素A，B和D是紧密的同源物，由天蚕素蛾的35中发现的35-39个残基组成。
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