Anaspec/Oxonol VI/100 mg/AS-84704
市场价：
¥3280.00
美元价：
1640.00
产品分类：
流式抗体
公司分类：
Flow_cytometry
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| Product Name | Oxonol VI[Bis - (3 - propyl - 5 - oxoisoxazol - 4 - yl)pentamethine oxonol] |
| Size | 100 mg |
| Catalog # | AS-84704 |
| US$ | $164 |
Oxonol VI is used as an optical indicator for membrane potentials in lipid vesicles. Oxonol VI is a sensitive slow-response membrane potential probe whose magnitude of optical response is much larger than that of faster response probes (Oxonol V). The fluorescence of Oxonol VI decreases upon membrane hyperpolarization. In general, slow response probes are suitable for detecting changes in average membrane potentials of nonexcitable cells caused by respiratory activity, ion-channel permeability, drug binding and other factors.
| |
| Detailed Information |  Datasheet Material Safety Data Sheets (MSDS) |
| Storage | -20°C desiccated and protected from light |
| References | 1. Cheng Z, et al. (2004).Am J Physiol Regul Integr Comp Physiol 286, R625-33.2. Koo YE, et al. (2004).Anal Chem 76, 2498-505. 3. Wu CC, et al. (2004).Cereb Cortex 14, 543-54.4. Suksaweang S, et al. (2004).Dev Biol 266, 109-22. 5. Iriyama A, et al. (2004). Invest Ophthalmol Vis Sci 45, 943-7. 6. Vest RS, et al. (2004).Biophys J 86, 2251-60.7. Zhang X and Kirsch LE (2004).Pharm Dev Technol 9, 219-27. 8. Hefnawy MA and Abou-Zeid AM (2003).Acta Microbiol Pol 52, 53-64.9. Jordan MB, et al. (2003).Blood 101, 594-601.10. Bianchi L, et al. (2003).J Biol Chem 278, 12415-24.11. deAzevedo LC, et al. (2003).J Neurobiol 55, 288-98.12. Ramani K and Balasubramanian SV (2003).Biochim Biophys Acta 1618, 67-78. |
| Molecular Weight | 316.352 |
| Molecular Formula | C17H20N2O4 |
| Spectral Properties | Abs/Em = 599/634 nm |
| Solvent System | DMSO |
| Product Citations | Mennerick, S. et al. (2010). Diverse Voltage-Sensitive Dyes Modulate GABAAReceptor Function. J Neurosci 30, 2871. |
品牌介绍
Anaspec阳离子抗菌肽是所有物种先天防御的重要组成部分。在许多生物中，包括真菌，昆虫，两栖动物和人类中，已经鉴定出100多种这些肽。这些疏水性和两亲性肽表现出抗生素，杀真菌，溶血，杀病毒和杀肿瘤活性。基于它们的结构特性，这些抗菌肽可分为三类：螺旋状肽，含有一个至几个二硫键的肽以及富含某些氨基酸（例如脯氨酸或色氨酸）的肽。这些肽大多数具有一些共同的特征，例如它们的低分子量（2-5 kDa），存在多个赖氨酸和精氨酸残基以及两亲性质。尽管尚不清楚它们杀死细菌的确切机制，但已表明导致膜渗透的肽-脂相互作用在其活性中起作用。抗生素肽的实例包括洋甘菊素，其由皮肤的皮肤分泌。非洲爪蟾 ; 人嗜中性粒细胞的防御素和人唾液中的组蛋白。天蚕素是由昆虫在感染条件下产生的。天蚕素A，B和D是紧密的同源物，由天蚕素蛾的35中发现的35-39个残基组成。
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