Anaspec/LCMV总成(61-80)/1mg/AS-64851
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¥2260.00
美元价:
1130.00
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3392242852
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4000-520-616
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商品介绍
Product Name | LCMV GP (61 - 80)GLKGPDIYKGVYQFKSVEFD |
Size | 1 mg |
Catalog # | AS-64851 |
US$ | $113 |
LCMV infection has been shown to induce a relatively strong T-helper response (at least in C57BL/6 mice) focused almost entirely upon two epitopes, GP6180 and NP309328, both of which are presented by I-Ab. The LCMV 61-80 peptide acts preferentially as an LCMV T helper epitope and this epitope seems to be processed differently (lysosomal-independent pathway) for viral cell-mediated targeting. | |
Detailed Information | Material Safety Data Sheets (MSDS) |
Storage | -20°C |
References | Rodriguez, F. et al. J Virol 75, 10421 (2001). |
Molecular Weight | 2290.6 |
GLKGPDIYKGVYQFKSVEFD | |
Sequence(Three-Letter Code) | H - Gly - Leu - Lys - Gly - Pro - Asp - Ile - Tyr - Lys - Gly - Val - Tyr - Gln - Phe - Lys - Ser - Val - Glu - Phe - Asp - OH |
Product Citations | Sahin, E. et al. (2015). Loss of phosphatase and tensin homolog in APCs impedes Th17-mediated autoimmune encephalomyelitis. J Immunol1952560 doi: 10.4049/jimmunol.1402511. |
品牌介绍
Anaspec阳离子抗菌肽是所有物种先天防御的重要组成部分。在许多生物中,包括真菌,昆虫,两栖动物和人类中,已经鉴定出100多种这些肽。这些疏水性和两亲性肽表现出抗生素,杀真菌,溶血,杀病毒和杀肿瘤活性。基于它们的结构特性,这些抗菌肽可分为三类:螺旋状肽,含有一个至几个二硫键的肽以及富含某些氨基酸(例如脯氨酸或色氨酸)的肽。这些肽大多数具有一些共同的特征,例如它们的低分子量(2-5 kDa),存在多个赖氨酸和精氨酸残基以及两亲性质。尽管尚不清楚它们杀死细菌的确切机制,但已表明导致膜渗透的肽-脂相互作用在其活性中起作用。抗生素肽的实例包括洋甘菊素,其由皮肤的皮肤分泌。非洲爪蟾 ; 人嗜中性粒细胞的防御素和人唾液中的组蛋白。天蚕素是由昆虫在感染条件下产生的。天蚕素A,B和D是紧密的同源物,由天蚕素蛾的35中发现的35-39个残基组成。
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