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当前位置: 首页 > 产品中心 > Cloning_and_expression > Anaspec/Tau Peptide (244 - 274) (Repeat 1 domain)/1 mg/AS-65433-1
商品详细Anaspec/Tau Peptide (244 - 274) (Repeat 1 domain)/1 mg/AS-65433-1
Anaspec/Tau Peptide (244 - 274) (Repeat 1 domain)/1 mg/AS-65433-1
Anaspec/Tau Peptide (244 - 274) (Repeat 1 domain)/1 mg/AS-65433-1
商品编号: AS-65433-1
品牌: Anaspec
市场价: ¥1480.00
美元价: 740.00
产地: 美国(厂家直采)
公司:
产品分类: 克隆和表达
公司分类: Cloning_and_expression
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
DescriptionSequence(One-Letter Code)
Product NameTau Peptide (244 - 274) (Repeat 1 domain)Ac - QTAPVPMPDLKNVKSKIGSTENLKHQPGGGK
Size1 mg
Catalog #AS-65433-1
US$$74
PurityPeak Area by HPLC ≥95%

TAU proteins belong to the microtubule-associated protein (MAP) family and are involved in the pathogenesis of Alzheimer’s disease. In the human brain, there are six TAU isoforms ranging from 352 to 441 amino acids in length. These isoforms vary at the carboxyl terminal according to the presence of either three repeat or four repeat domains (R1-R4), in addition to the presence or absence of one or two insert domains at the amino-terminus (see figure below). Tau Peptide (244-274) is a 31-amino acid long peptide derived from the Repeat 1 domain.RELATED PRODUCTS:

Tau Peptide (45-73) (Exon 2/Insert 1 domain)Tau Peptide (74-102) (Exon 3/Insert 2 domain)Tau Peptide (275-305) (Repeat 2 domain)Tau Peptide (306-336) (Repeat 3 domain)Tau Peptide (337-368) (Repeat 4 domain)
ImagesTau Peptide (244-274) (Repeat 1 domain)
Detailed InformationDatasheet
Material Safety Data Sheets (MSDS)
Storage-20°C
ReferencesBuee, L. et al. Brain Res Rev 33 95 (2000); Trinczek, B. et al. Mol Biol Cell 6, 1887 (1995).
Molecular Weight3299.83
Ac-QTAPVPMPDLKNVKSKIGSTENLKHQPGGGK
Sequence(Three-Letter Code)Ac - Gln - Thr - Ala - Pro - Val - Pro - Met - Pro - Asp - Leu - Lys - Asn - Val - Lys - Ser - Lys - Ile - Gly - Ser - Thr - Glu - Asn - Leu - Lys - His - Gln - Pro - Gly - Gly - Gly - Lys - OH
品牌介绍
Anaspec阳离子抗菌肽是所有物种先天防御的重要组成部分。在许多生物中,包括真菌,昆虫,两栖动物和人类中,已经鉴定出100多种这些肽。这些疏水性和两亲性肽表现出抗生素,杀真菌,溶血,杀病毒和杀肿瘤活性。基于它们的结构特性,这些抗菌肽可分为三类:螺旋状肽,含有一个至几个二硫键的肽以及富含某些氨基酸(例如脯氨酸或色氨酸)的肽。这些肽大多数具有一些共同的特征,例如它们的低分子量(2-5 kDa),存在多个赖氨酸和精氨酸残基以及两亲性质。尽管尚不清楚它们杀死细菌的确切机制,但已表明导致膜渗透的肽-脂相互作用在其活性中起作用。抗生素肽的实例包括洋甘菊素,其由皮肤的皮肤分泌。非洲爪蟾 ; 人嗜中性粒细胞的防御素和人唾液中的组蛋白。天蚕素是由昆虫在感染条件下产生的。天蚕素A,B和D是紧密的同源物,由天蚕素蛾的35中发现的35-39个残基组成。