Anaspec/类固醇受体辅活化因子-1（SRC-1），（676-700），生物素标记/1mg/AS-62152
市场价：
¥4980.00
美元价：
2490.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| Product Name | Steroid Receptor Coactivator - 1 (SRC - 1), (676 - 700), biotin labeledBiotin - CPSSHSSLTERHKILHRLLQEGSPS |
| Size | 1 mg |
| Catalog # | AS-62152 |
| US$ | $249 |
| Purity | % Peak Area By HPLC ≥ 95% |
This is amino acids 676 to 700 fragment of steroid receptor co-activator (SRC1). This N-terminnaly biotinylated peptide is derived from the second LXXLL motif ofSRC1. Co-activator proteins interact with nuclear receptors in a ligand-dependent manner and augment transcription. A short amphipathic beta-helical domain that includes this LXXLL motif serves as the interaction interface between the co-activator molecules and the ligand-dependent activation function (AF-2) located in the COOH-terminus of the nuclear receptor ligand-binding domain (LBD). Receptor binding domain of the co-activator SRC-1 is specifically recruited to the farnesoid X receptor (FXR) ligand-binding domain. | |
| Detailed Information |  Material Safety Data Sheets (MSDS) |
| Storage | -20°C |
| Molecular Weight | 3026.5 |
| Biotin-CPSSHSSLTERHKILHRLLQEGSPS | |
| Sequence(Three-Letter Code) | Biotin - Cys - Pro - Ser - Ser - His - Ser - Ser - Leu - Thr - Glu - Arg - His - Lys - Ile - Leu - His - Arg - Leu - Leu - Gln - Glu - Gly - Ser - Pro - Ser - OH |
品牌介绍
Anaspec阳离子抗菌肽是所有物种先天防御的重要组成部分。在许多生物中，包括真菌，昆虫，两栖动物和人类中，已经鉴定出100多种这些肽。这些疏水性和两亲性肽表现出抗生素，杀真菌，溶血，杀病毒和杀肿瘤活性。基于它们的结构特性，这些抗菌肽可分为三类：螺旋状肽，含有一个至几个二硫键的肽以及富含某些氨基酸（例如脯氨酸或色氨酸）的肽。这些肽大多数具有一些共同的特征，例如它们的低分子量（2-5 kDa），存在多个赖氨酸和精氨酸残基以及两亲性质。尽管尚不清楚它们杀死细菌的确切机制，但已表明导致膜渗透的肽-脂相互作用在其活性中起作用。抗生素肽的实例包括洋甘菊素，其由皮肤的皮肤分泌。非洲爪蟾 ; 人嗜中性粒细胞的防御素和人唾液中的组蛋白。天蚕素是由昆虫在感染条件下产生的。天蚕素A，B和D是紧密的同源物，由天蚕素蛾的35中发现的35-39个残基组成。
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