Anaspec/SARS-CoV肽抗原/1mg净肽/AS-65628
市场价:
¥5800.00
美元价:
2900.00
产品分类:
抗猪
公司分类:
Anti_Swine
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
Product Name | SARS - CoV Peptide AntigenNEWVLNDILSRL |
Size | 1 mg NET peptide |
Catalog # | AS-65628 |
US$ | $290 |
Purity | % Peak Area By HPLC ≥ 95% |
This peptide from the Spike (S) protein of SARS-CoV is a naturally processed epitope shown to induce specific CTLs. The peptide epitope was validated in binding assay to HLA-A2 of T2 cell line. It also induced specific CD8+ T-cell responses against SARS-CoV. This peptide sequence is also seen within the spike glycoprotein of SARS-CoV2. | |
Detailed Information | DatasheetMaterial Safety Data Sheets (MSDS) |
Storage | -20°C |
References | 1. Lv Y, et al. Identification of a novel conserved HLA-A*0201-restricted epitope from the spike protein of SARS-CoV. BMC immunology.2009 Dec 1;10(1):61.2. Grifoni A et al. A sequence homology and bioinformatic approachcan predict candidate targets for immune responses to SARS-CoV-2. Cell host& microbe. 2020 Mar 16.3. Ahmed SF et al. Preliminary identification of potential vaccine targetsfor the COVID-19 coronavirus (SARS-CoV-2) based on SARS-CoV immunologicalstudies. Viruses. 2020 Mar;12(3):254. |
Molecular Weight | 1042.2 |
VLNDILSRL | |
Sequence(Three-Letter Code) | H - Val - Leu - Asn - Asp - Ile - Leu - Ser - Arg - Leu - OH |
品牌介绍
Anaspec阳离子抗菌肽是所有物种先天防御的重要组成部分。在许多生物中,包括真菌,昆虫,两栖动物和人类中,已经鉴定出100多种这些肽。这些疏水性和两亲性肽表现出抗生素,杀真菌,溶血,杀病毒和杀肿瘤活性。基于它们的结构特性,这些抗菌肽可分为三类:螺旋状肽,含有一个至几个二硫键的肽以及富含某些氨基酸(例如脯氨酸或色氨酸)的肽。这些肽大多数具有一些共同的特征,例如它们的低分子量(2-5 kDa),存在多个赖氨酸和精氨酸残基以及两亲性质。尽管尚不清楚它们杀死细菌的确切机制,但已表明导致膜渗透的肽-脂相互作用在其活性中起作用。抗生素肽的实例包括洋甘菊素,其由皮肤的皮肤分泌。非洲爪蟾 ; 人嗜中性粒细胞的防御素和人唾液中的组蛋白。天蚕素是由昆虫在感染条件下产生的。天蚕素A,B和D是紧密的同源物,由天蚕素蛾的35中发现的35-39个残基组成。
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