Anaspec/Phytochelatin 4, PC4/1 mg/AS-60789
市场价：
¥3180.00
美元价：
1590.00
产品分类：
组织标本
公司分类：
Tissue_samples
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| Product Name | Phytochelatin 4, PC4(γE - C)4 - G |
| Size | 1 mg |
| Catalog # | AS-60789 |
| US$ | $159 |
| Purity | % Peak Area By HPLC ≥ 95% |
A glutathione-derived heavy metal-detoxifying peptide of higher plants consisting of 4 units of γGlu-Cys. | |
| Detailed Information |  Datasheet Material Safety Data Sheets (MSDS) |
| Storage | -20°C |
| References | Grill, E. et al. Science 230, 674 (1985); Rauser, WE. Plant Physiol. 109, 1141 (1995). |
| Molecular Weight | 1004.1 |
| (γE-C)4-G | |
| Sequence(Three-Letter Code) | H - γ - Glu - Cys - γ - Glu - Cys - γ - Glu - Cys - γ - Glu - Cys - Gly - OH |
| Product Citations | Mohan, T. et al. (2016).Cytokinin Determines Thiol-Mediated Arsenic Tolerance and Accumulation.ASPGDOI: https://doi.org/10.1104/pp.16.00372Dresler, S. et al. (2014). Effect of cadmium on selected physiological and morphological parameters in metallicolous and non-metallicolous populations of Echium vulgare . Ecotoxicol Environ Safety 104, 332. doi: 10.1016/j.ecoenv.2014.03.019.Fischer, S. et al. (2014). Analysis of plant Pb tolerance at realistic submicromolar concentrations demonstrates the role of phytochelatin synthesis for Pb detoxification. Environ Sci Technol 48, 7552. doi: 10.1021/es405234p.Ke, C-Y. et al. (2014). Understanding of thiol-induced etching of luminescent gold nanoclusters. RSC Adv 4, 26050. doi: 10.1039/C4RA02111H. Spisso, AA. et al. (2014). Characterization of Hg-phytochelatins complexes in vines (Vitis vinifera cv Malbec) as defense mechanism against metal stress.BioMetals 27, 591.Abboud, P. and KJ. Wilkinson. (2013). Role of metal mixtures (Ca, Cu and Pb) on Cd bioaccumulation and phytochelatin production by Chlamydomonas reinhardtii. Environ Pollution 179, 33. doi:10.1016/j.envpol.2013.03.047Miszczak, A. et al. (2013). SEC ICP MS and CZE ICP MS investigation of medium and high molecular weight complexes formed by cadmium ions with phytochelatins. Anal Bioanal Chem 405, 4667. doi: 10.1007/s00216-013-6868-3.Rigouin, C. et al. (2013). Characterization of the phytochelatin synthase from the human parasitic nematode Ancylostoma ceylanicum.Mol Biochem Parasitol 191, 1. doi: 10.1016/j.molbiopara.2013.07.003.Rigouin, C. et al. (2013). Towards an understanding of the function of the phytochelatin synthase of Schistosoma mansoni. PLoS Neglected Tropical Dis 7,e2037. doi: 10.1371/journal.pntd.0002037.Akhter, MF. et al. (2012). Reduced translocation of cadmium from roots is associated with increased production of phytochelatins and their precursors. J Plant Physiol 169, 1821. doi: 10.1016/j.plaphy.2011.10.007.Fernández, R. et al. (2012). Lead accumulation and synthesis of non-protein thiolic peptides in selected clones of Melilotus alba and Melilotus officinalis. Environ Exp Botany 78, 18. doi: 10.1016/j.envexpbot.2011.12.016.Huang, J. et al. (2012). Fission yeast HMT1 lowers seed cadmium through phytochelatin-dependent vacuolar sequestration in Arabidopsis. Plant Physiol 158,1779.Lavoie, M. et al. (2012). The influence of pH on algal cell membrane permeability and its implications for the uptake of lipophilic metal complexes. J Phycol 48, 293. doi: 10.1111/j.1529-8817.2012.01126.xSantini, O., et al. (2012). Phytochelatins in the freshwater bivalve Anodonta cygnea." Effects of copper on calcium metabolism and detoxification mechanisms in freshwater bivalve species of Anodonta: 108.Shen, C-C. et al. (2012). Selective extraction of thiol-containing peptides in seawater using Tween 20-capped gold nanoparticles followed by capillary electrophoresis with laser-induced fluorescence. J Chromatogr A 1220, 162. doi: 10.1016/j.chroma.2011.11.057.Wu, Y. and W-X. Wang. (2012). Thiol compounds induction kinetics in marine phytoplankton during and after mercury exposure. J Haz Mat 217, 271. doi: 10.1016/j.jhazmat.2012.03.024.Carrasco-Gil, S. et al. (2011). Complexation of Hg with phytochelatins is important for plant Hg tolerance. Plant Cell Environ 34 778. doi: 10.1111/j.1365-3040.2011.02281.x.Heikal, L. et al. (2011). S-nitrosophytochelatins: investigation of the bioactivity of an oligopeptide nitric oxide delivery system. Biomacromol 12 2103. doi: 10.1021/bm200159h.Zeng, X-W. et al. (2011). Effects of Zn on plant tolerance and non-protein thiol accumulation in Zn hyperaccumulator Arabis paniculata Franch. Environ Exp Botany 70, 227. doi: 10.1016/j.envexpbot.2010.09.009.Elviri, L., et al. (2010). Identification of in vivo nitrosylated phytochelatins in Arabidopsis thaliana cells by liquid chromatography-direct electrospray-linear ion trap-mass spectrometry. J Chrom A 1217, 4120. doi: 10.1016/j.chroma.2010.02.013.Elviri, L. et al. (2010). Identification of in vivo nitrosylated phytochelatins in Arabidopsis thaliana cells by liquid chromatography-direct electrospray-linear ion trap-mass spectrometry. J Chromatog 1217, 4120.Liedschulte, V. et al. (2010). Exploiting plants for glutathione (GSH) production: uncoupling GSH synthesis from cellular controls results in unprecedented GSH accumulation. Plant Biotechnol J 8 807. doi: 10.1111/j.1467-7652.2010.00510.x.Wang, M-J. and W-X. Wang. (2009). Cadmium in three marine phytoplankton: accumulation, subcellular fate and thiol induction. Aquatic Toxicol 95, 99. doi: 10.1016/j.aquatox.2009.08.006.Kang, SH. et al. (2008). Microbial synthesis of CdS nanocrystals in genetically engineered E. coli. Angewandte Chem Int Ed 47, 5186. doi: 10.1002/anie.200705806.Mendoza‐Cózatl, DG. et al. (2008). Identification of high levels of phytochelatins, glutathione and cadmium in the phloem sap of Brassica napus. A role for thiol‐peptides in the long‐distance transport of cadmium and the effect of cadmium on iron translocation. Plant J 54, 249. doi: 10.1111/j.1365-313X.2008.03410.x.Zeng, X. et al. (2008). Responses of non-protein thiols to Cd exposure in Cd hyperaccumulator Arabis paniculata Franch. Environ. Exp. Botany 66, 242.Miao, AJ. & WX. Wang (2007). Predicting copper toxicity with its intracellular or subcellular concentration and the thiol synthesis in a marine diatom. Environ. Sci. Technol. 41, 1777. |
品牌介绍
Anaspec阳离子抗菌肽是所有物种先天防御的重要组成部分。在许多生物中，包括真菌，昆虫，两栖动物和人类中，已经鉴定出100多种这些肽。这些疏水性和两亲性肽表现出抗生素，杀真菌，溶血，杀病毒和杀肿瘤活性。基于它们的结构特性，这些抗菌肽可分为三类：螺旋状肽，含有一个至几个二硫键的肽以及富含某些氨基酸（例如脯氨酸或色氨酸）的肽。这些肽大多数具有一些共同的特征，例如它们的低分子量（2-5 kDa），存在多个赖氨酸和精氨酸残基以及两亲性质。尽管尚不清楚它们杀死细菌的确切机制，但已表明导致膜渗透的肽-脂相互作用在其活性中起作用。抗生素肽的实例包括洋甘菊素，其由皮肤的皮肤分泌。非洲爪蟾 ; 人嗜中性粒细胞的防御素和人唾液中的组蛋白。天蚕素是由昆虫在感染条件下产生的。天蚕素A，B和D是紧密的同源物，由天蚕素蛾的35中发现的35-39个残基组成。
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