Anaspec/OVA（323-339）/1mg/AS-27024
市场价：
¥2300.00
美元价：
1150.00
产品分类：
重组蛋白
公司分类：
Recombinant_protein
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| Product Name | OVA (323 - 339)ISQAVHAAHAEINEAGR |
| Size | 1 mg |
| Catalog # | AS-27024 |
| US$ | $115 |
| Purity | % Peak Area By HPLC ≥ 95% |
An H-2b-restricted OVA class II epitope. | |
| Detailed Information |  Datasheet Material Safety Data Sheets (MSDS) |
| Storage | -20°C |
| References | Oran, A. and H. Robinson, J. Immunol. 171, 1999 (2003); Palmiter, RD. et al. Proc. Natl. Acad. Sci. 75, 94 (1978). |
| Molecular Weight | 1773.9 |
| ISQAVHAAHAEINEAGR | |
| Sequence(Three-Letter Code) | H - Ile - Ser - Gln - Ala - Val - His - Ala - Ala - His - Ala - Glu - Ile - Asn - Glu - Ala - Gly - Arg - OH |
| Product Citations | Ma, J. et al. (2012). Dectin-1-triggered recruitment of light chain 3 protein to phagosomes facilitates major histocompatibility complex class II presentation of fungal-derived antigens J Biol Chem doi: 10.1074/jbc.M112.382812.Su, W. et al. (2012). Synthesized OVA323-339MAP octamers mitigate OVA-induced airway inflammation by regulating Foxp3 T regulatory cells BMC Immunol doi: 10.1186/1471-2172-13-34.Zhang, W. et al. (2012). Assessment of the innate and adaptive immune system in proliferative vitreoretinopathy Nat. doi: 10.1038/eye.2012.52.Barberi, T. et al. (2012). The prolyl isomerase Pin1 modulates development of CD8+ cDC in mice PLoS One doi: 10.1371/journal.pone.0029808.Steinbach, E.C. et al. (2014). Innate PI3K p110δ regulates Th1/Th17 development and microbiota-dependent colitis J Immunol doi: 10.4049/jimmunol.1301533 .He, H. et al. (2014). In vivo downregulation of innate and adaptive immune responses in corneal allograft rejection by HC-HA/PTX3 complex purified from amniotic membrane iovs 55 1647. doi: 10.1167/iovs.13-13094. Koguchi, Y. et al. (2012). Preformed CD40L is stored in Th1, Th2, Th17, and T follicular helper cells as well as CD4+8− thymocytes andinvariant NKT cells but not in treg cells PLoS One doi: 10.1371/journal.pone.0031296.Barkauskas, DS. et al. (2015). Focal transient CNS vessel leak provides a tissue niche for sequential immune cell accumulation during the asymptomatic phase of EAE induction. Exp Neurol doi:10.1016/j.expneurol.2015.02.018.Hütter, J. et al. (2013). Toward animal cell culturebased Influenza vaccine design: Viral hemagglutinin N-glycosylation markedly impacts immunogenicity. J Immunol 190, 220. doi: 10.4049/jimmunol.1201060.Jin, H. et al. (2013). Neddylation pathway regulates T-cell function by targeting an adaptor protein Shc and a protein kinase Erk signaling. PNAS 110, 624. doi: 10.1073/pnas.1213819110.Lau-Kilby, A. et al. (2011). Interleukin-2 inhibits FMS-like tyrosine kinase 3 receptor ligand (flt3L)-dependent development and function of conventional and plasmacytoid dendritic cells. PNAS 10.1073/pnas.1009738108.Zhou, H. et al. (2011). The secretions products from invading cercariae of S. japonicum (0-3hRP) restrain mouse dendritic cells to mature. Parastiol Res 10.1007/s00436-011-2458-5.Durgan, K. et al. (2010). Targeting NKT cells and PD-L1 pathway results in augmented anti-tumor responses in a melanoma model. Cancer Immunol Immunotherapy 10.1007/s00262-010-0963-5.Falcon, C. et al. (2010). Excretory-secretory products (ESP) from Fasciola hepatica induce tolerogenic properties in myeloid dendritic cells.Vet Immunol Immunopathol 10.1016/j.vetimm.2010.04.007.Garrod, KR. et al. (2010). NK Cell patrolling and elimination of donor-derived dendritic cells favor indirect alloreactivity. J Immunol 184, 2329.Harada, Y. et al. (2010). Transcription factors Foxo3a and Foxo1 couple the E3 ligase Cbl-b to the induction of Foxp3 expression in induced regulatory T cells. JEM doi: 10.1084/jem.20100004.Toubai, T. et al. (2010). Immunization with host-type CD8{alpha}+ dendritic cells reduces experimental acute GVHD in an IL-10dependent manner. Blood 115, 724.Zhong, W. et al. (2010) OX40 induces CCL20 expression in the context of antigen stimulation: An expanding role of co-stimulatory molecules in chemotaxis. Cytokine 50, 253Guarda, G. et al. (2009). T cells dampen innate immune responses through inhibition of NLRP1 and NLRP3 inflammasomes. Nature 460, 269.Liu, J. et al. (2009). Characterizing of respiratory syncytial virus M- and M2-specific CD4 T cells in a murine model. J Virol 83, 4934.Mahon, R. et al. (2009). Mycobacterium tuberculosis cell wall glycolipids directly inhibit CD4+ T cell activation by interfering with proximal T cell receptors signaling. Infect Immun 10.1128/IAI.00222-09.Ocana-Morgner, C. et al. (2009). Swap-70 regulates RhoA/RhoB-dependent MHCII surface localization in dendritic cells. Blood 113, 1474.Kang, Y. et al. (2008). Cutting Edge: immunosuppressant as adjuvant for tolerogenic immunization. J Immunol 180, 5172.Siracusa, MC. et al. (2008). Dynamics of lung macrophage activation in response to helminth infection. J Leukocyte Biol 84, 1422.Wang, L. et al. (2008). Programmed death 1 ligand signaling regulates the generation of adaptive Foxp3+CD4+ regulatory T cells. PNAS 105, 9331.Kwa, S-F. et al. (2006). Peyer"s patches are required for the induction of rapid Th1 responses in the gut and mesenteric lymph nodes during an enteric infection. J Immunol 176, 7533.Stachowiak, AN. et al. (2006). Homeostatic lymphoid chemokines synergize with adhesion ligands to trigger T and B lymphocyte chemokinesis. J Immunol 177, 2340.Garrod, KR. et al. (2006). Targeted lymphoid homing of dendritic cells is required for prolongation of allograft survival. J Immunol 177, 863.Baekkevold, ES. (2005). A role for CCR4 in development of mature circulating cutaneous T helper memory cell populations. J Exp Med 201, 1045.Seroogy, CM. et al. (2004). The gene related to anergy in lymphocytes, an E3 ubiquitin ligase, is necessary for anergy induction in CD4 T Cells. J Immunol 173, 79.Dorsam, G. et al. (2003). Transduction of multiple effects of sphingosine 1-phosphate (S1P) on T cell functions by the S1P1 G protein-coupled receptor. J Immunol 171, 3500.Bard, F. et al. (2003). Epitope and isotype specificities of antibodies to β-amyloid peptide for protection against Alzheimer"s disease-like neuropathology. PNAS 100, 2023. |
品牌介绍
Anaspec阳离子抗菌肽是所有物种先天防御的重要组成部分。在许多生物中，包括真菌，昆虫，两栖动物和人类中，已经鉴定出100多种这些肽。这些疏水性和两亲性肽表现出抗生素，杀真菌，溶血，杀病毒和杀肿瘤活性。基于它们的结构特性，这些抗菌肽可分为三类：螺旋状肽，含有一个至几个二硫键的肽以及富含某些氨基酸（例如脯氨酸或色氨酸）的肽。这些肽大多数具有一些共同的特征，例如它们的低分子量（2-5 kDa），存在多个赖氨酸和精氨酸残基以及两亲性质。尽管尚不清楚它们杀死细菌的确切机制，但已表明导致膜渗透的肽-脂相互作用在其活性中起作用。抗生素肽的实例包括洋甘菊素，其由皮肤的皮肤分泌。非洲爪蟾 ; 人嗜中性粒细胞的防御素和人唾液中的组蛋白。天蚕素是由昆虫在感染条件下产生的。天蚕素A，B和D是紧密的同源物，由天蚕素蛾的35中发现的35-39个残基组成。
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