Anaspec/增食欲素B,人/1 mg/AS-65573
市场价:
¥5260.00
美元价:
2630.00
产品分类:
基因编辑
公司分类:
gene_editing
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3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
Product Name | Orexin B, human |
Size | 1 mg |
Catalog # | AS-65573 |
US$ | $263 |
Purity | Peak Area by HPLC ≥95% |
Orexins are synthesized by posterolateral neurons in hypothalamus. They bind to orexin-1 (OxR1) and orexin 2 (OxR2) receptors. Orexin A can bind to both OxR1 and OxR2 while Orexin B can associate with OxR2 only. Both Orexins are involved in the regulation of arousal and sleep states, energy homeostasis, and autonomic central control. | |
Detailed Information | DatasheetMaterial Safety Data Sheets (MSDS) |
Storage | 20°C |
References | 1. Martynska L., et.al., Neuroendocr Lett 4(26), 289-292 (2005).2. Ebrahim I.O., et.al., J of Royl Soc of Med95, 227-230 (2002).3. Ramanjaneya M., et.al., Endocrinology151 (7), 3169-3180 (2010). |
Molecular Weight | 2898.9 |
RSGPPGLQGRLQRLLQASGNHAAGILTM-NH2 | |
Sequence(Three-Letter Code) | Arg - Ser - Gly - Pro - Pro - Gly - Leu - Gln - Gly - Arg - Leu - Gln - Arg - Leu - Leu - Gln - Ala - Ser - Gly - Asn - His - Ala - Ala - Gly - Ile - Leu - Thr - Met - NH2 |
品牌介绍
Anaspec阳离子抗菌肽是所有物种先天防御的重要组成部分。在许多生物中,包括真菌,昆虫,两栖动物和人类中,已经鉴定出100多种这些肽。这些疏水性和两亲性肽表现出抗生素,杀真菌,溶血,杀病毒和杀肿瘤活性。基于它们的结构特性,这些抗菌肽可分为三类:螺旋状肽,含有一个至几个二硫键的肽以及富含某些氨基酸(例如脯氨酸或色氨酸)的肽。这些肽大多数具有一些共同的特征,例如它们的低分子量(2-5 kDa),存在多个赖氨酸和精氨酸残基以及两亲性质。尽管尚不清楚它们杀死细菌的确切机制,但已表明导致膜渗透的肽-脂相互作用在其活性中起作用。抗生素肽的实例包括洋甘菊素,其由皮肤的皮肤分泌。非洲爪蟾 ; 人嗜中性粒细胞的防御素和人唾液中的组蛋白。天蚕素是由昆虫在感染条件下产生的。天蚕素A,B和D是紧密的同源物,由天蚕素蛾的35中发现的35-39个残基组成。
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