Anaspec/神经肽Y,人,大鼠/1 mg/AS-22465
市场价:
¥3720.00
美元价:
1860.00
产品分类:
基因编辑
公司分类:
gene_editing
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
Product Name | Neuropeptide Y, human, ratYPSKPDNPGEDAPAEDMARYYSALRHYINLITRQRY - NH2 |
Size | 1 mg |
Catalog # | AS-22465 |
US$ | $186 |
Purity | % Peak Area By HPLC ≥ 95% |
Detailed Information | DatasheetMaterial Safety Data Sheets (MSDS) |
Storage | -20°C |
References | Ref: Minth, C. et al. Proc. Natl. Acad. Sci. USA 81, 4577 (1984). |
Molecular Weight | 4271.8 |
YPSKPDNPGEDAPAEDMARYYSALRHYINLITRQRY-NH2 | |
Sequence(Three-Letter Code) | H - Tyr - Pro - Ser - Lys - Pro - Asp - Asn - Pro - Gly - Glu - Asp - Ala - Pro - Ala - Glu - Asp - Met - Ala - Arg - Tyr - Tyr - Ser - Ala - Leu - Arg - His - Tyr - Ile - Asn - Leu - Ile - Thr - Arg - Gln - Arg - Tyr - NH2 |
Product Citations | Shrivastava, A. et al. (2013). Heterobivalent dual-target probe for targeting GRP and Y1 receptors on tumor cells. Bioorg Med Chem Lett 23, 687. doi: 10.1016/j.bmcl.2012.11.110.Pelz, KM. & J. Dark (2007). ICV NPY Y1 receptor agonist but not Y5 agonist induces torpor-like hypothermia in cold-acclimated Siberian hamsters. Am J Physiol Regulatory Integrative Comp Physiol 292, R2299.Gao, J. et al. (2004). Selective activation of central NPY Y1 vs. Y5 receptor elicits hyperinsulinemia via distinct mechanisms. Am J Physiol Endocrinol Metab 287, E706. doi: 10.1152/ajpendo.00530.2003.Kapoor, JR. and CD. Sladek. (2001). Substance P and NPY differentially potentiate ATP and adrenergic stimulated vasopressin and oxytocin release. Am J Physiol Regul Integr Comp Physiol 280, R69. |
品牌介绍
Anaspec阳离子抗菌肽是所有物种先天防御的重要组成部分。在许多生物中,包括真菌,昆虫,两栖动物和人类中,已经鉴定出100多种这些肽。这些疏水性和两亲性肽表现出抗生素,杀真菌,溶血,杀病毒和杀肿瘤活性。基于它们的结构特性,这些抗菌肽可分为三类:螺旋状肽,含有一个至几个二硫键的肽以及富含某些氨基酸(例如脯氨酸或色氨酸)的肽。这些肽大多数具有一些共同的特征,例如它们的低分子量(2-5 kDa),存在多个赖氨酸和精氨酸残基以及两亲性质。尽管尚不清楚它们杀死细菌的确切机制,但已表明导致膜渗透的肽-脂相互作用在其活性中起作用。抗生素肽的实例包括洋甘菊素,其由皮肤的皮肤分泌。非洲爪蟾 ; 人嗜中性粒细胞的防御素和人唾液中的组蛋白。天蚕素是由昆虫在感染条件下产生的。天蚕素A,B和D是紧密的同源物,由天蚕素蛾的35中发现的35-39个残基组成。
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