Anaspec/生物素-神经颗粒蛋白（48-76），小鼠/1mg/AS-65577
市场价：
¥7160.00
美元价：
3580.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| Product Name | biotin - Neurogranin (48 - 76), mouse |
| Size | 1 mg |
| Catalog # | AS-65577 |
| US$ | $358 |
| Purity | Peak Area by HPLC ≥95% |
Neurogranin is a post synaptic protein that is expressed in dendritic cytoplasm. It modulates calcium-mediated signaling pathways and plays critical role in synaptic plasticity. Recently Neurogranin (48-76) was identified as a major neurogranin peptide fragment in human brain and it was found that patients with Alzheimers Disease have elevated levels of Neurogranin (48-76) in cerebrospinal fluid. | |
| Detailed Information |  Datasheet Material Safety Data Sheets (MSDS) |
| Storage | This peptide is shipped at ambient temperature. Upon receipt, store lyophilized peptide at 20°C or lower. Reconstituted peptide can be aliquoted and stored at 20°C or lower. |
| References | 1.De Vos A., et.al., Alzh and Dement 4, 1-9 (2015) |
| Molecular Weight | 2548.9 |
| Biotin-SGECGRKGPGPGGPGGAGGARGGAGGGPS | |
| Sequence(Three-Letter Code) | biotin - Ser - Gly - Glu - Cys - Gly - Arg - Lys - Gly - Pro - Gly - Pro - Gly - Gly - Pro - Gly - Gly - Ala - Gly - Gly - Ala - Arg - Gly - Gly - Ala - Gly - Gly - Gly - Pro - Ser - OH |
品牌介绍
Anaspec阳离子抗菌肽是所有物种先天防御的重要组成部分。在许多生物中，包括真菌，昆虫，两栖动物和人类中，已经鉴定出100多种这些肽。这些疏水性和两亲性肽表现出抗生素，杀真菌，溶血，杀病毒和杀肿瘤活性。基于它们的结构特性，这些抗菌肽可分为三类：螺旋状肽，含有一个至几个二硫键的肽以及富含某些氨基酸（例如脯氨酸或色氨酸）的肽。这些肽大多数具有一些共同的特征，例如它们的低分子量（2-5 kDa），存在多个赖氨酸和精氨酸残基以及两亲性质。尽管尚不清楚它们杀死细菌的确切机制，但已表明导致膜渗透的肽-脂相互作用在其活性中起作用。抗生素肽的实例包括洋甘菊素，其由皮肤的皮肤分泌。非洲爪蟾 ; 人嗜中性粒细胞的防御素和人唾液中的组蛋白。天蚕素是由昆虫在感染条件下产生的。天蚕素A，B和D是紧密的同源物，由天蚕素蛾的35中发现的35-39个残基组成。
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