阿纳斯佩克/MOTS-c/1毫克/AS-65587
								
								
										市场价:
										¥3060.00
									
									
										美元价:
										1530.00
									
								
										产品分类:
										数字PCR系统
									
									
										公司分类:
										Digital_PCR_system
									
								
										联系Q Q:
										3392242852
									
									
										电话号码:
										4000-520-616
									
								
										电子邮箱:
										info@ebiomall.com
									
									商品介绍
						| Product Name | MOTS - cH - MRWQEMGYIFYPRKLR - OH | 
| Size | 1 mg | 
| Catalog # | AS-65587 | 
| US$ | $153 | 
| Purity | % Peak Area By HPLC ≥ 95% | 
Recent advances in high-resolution sequencing have led to the discovery of unique peptides derived from mitochondrial genome.1-2 Currently 8 peptides are identified: humanin, mitochondrial open reading frame of the 12S tRNA-c (MOTS-c), and six small humanin-like peptides (SHLP1-6). 1-2 All of these peptides are released into cytosol from mitochondria and associate with increased longevity and cell viability, reduced apoptosis, and other beneficial functions. 1-3MOTS-c was found to reduce insulin resistance, decrease obesity, and promote homeostasis. 3  | |
| Detailed Information | |
| Storage | -20°C | 
| References | 1. Cobb L. J. et al., AGING 8 (4), 796-808 (2016). 2. Okada A. K. et al., Sci Reports 7 (7802), 1-10 (2017). 3. Lee C., et al., Cell Met 21, 443-454 (2015). | 
| Molecular Weight | 2174.7 | 
| H-MRWQEMGYIFYPRKLR-OH | |
| Sequence(Three-Letter Code) | NH2 - Met - Arg - Trp - Gln - Glu - Met - Gly - Tyr - Ile - Phe - Tyr - Pro - Arg - Lys - Leu - Arg -COOH | 
品牌介绍
						Anaspec阳离子抗菌肽是所有物种先天防御的重要组成部分。在许多生物中,包括真菌,昆虫,两栖动物和人类中,已经鉴定出100多种这些肽。这些疏水性和两亲性肽表现出抗生素,杀真菌,溶血,杀病毒和杀肿瘤活性。基于它们的结构特性,这些抗菌肽可分为三类:螺旋状肽,含有一个至几个二硫键的肽以及富含某些氨基酸(例如脯氨酸或色氨酸)的肽。这些肽大多数具有一些共同的特征,例如它们的低分子量(2-5 kDa),存在多个赖氨酸和精氨酸残基以及两亲性质。尽管尚不清楚它们杀死细菌的确切机制,但已表明导致膜渗透的肽-脂相互作用在其活性中起作用。抗生素肽的实例包括洋甘菊素,其由皮肤的皮肤分泌。非洲爪蟾 ; 人嗜中性粒细胞的防御素和人唾液中的组蛋白。天蚕素是由昆虫在感染条件下产生的。天蚕素A,B和D是紧密的同源物,由天蚕素蛾的35中发现的35-39个残基组成。
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