Anaspec/NY - ESO - 1 (87 - 111)/1 mg/AS-62655
市场价:
¥4080.00
美元价:
2040.00
产品分类:
温度计
公司分类:
Thermometer
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3392242852
电话号码:
4000-520-616
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info@ebiomall.com
商品介绍
Product Name | NY - ESO - 1 (87 - 111)LLEFYLAMPFATPMEAELARRSLAQ |
Size | 1 mg |
Catalog # | AS-62655 |
US$ | $204 |
Purity | % Peak Area By HPLC ≥ 95% |
This is amino acids 81 to 111 fragment of the NY-ESO-1. The NY-ESO-1 antigen is expressed by many tumors of different histological types (including breast, prostate, lung, and melanoma) and by male germline cells, but not by other normal tissues. NY-ESO-1 encodes MHC class I- and class II-restricted peptides expressed by a diverse range of cancers and recognized by T cells. This peptide is pan-MHC class II-restricted sequence that is capable of binding to multiple HLA-DR and HLA-DP4 molecules, including HLA-DRB1*0101, 0401, 0701, and 1101 and HLA-DPB1*0401 and 0402 molecules. | |
Detailed Information | Material Safety Data Sheets (MSDS) |
Storage | -20°C |
References | Mandic, M. et al. J. Immunol. 174, 1751 (2005). |
Molecular Weight | 2869.4 |
LLEFYLAMPFATPMEAELARRSLAQ | |
Sequence(Three-Letter Code) | H - Leu - Leu - Glu - Phe - Tyr - Leu - Ala - Met - Pro - Phe - Ala - Thr - Pro - Met - Glu - Ala - Glu - Leu - Ala - Arg - Arg - Ser - Leu - Ala - Gln - OH |
品牌介绍
Anaspec阳离子抗菌肽是所有物种先天防御的重要组成部分。在许多生物中,包括真菌,昆虫,两栖动物和人类中,已经鉴定出100多种这些肽。这些疏水性和两亲性肽表现出抗生素,杀真菌,溶血,杀病毒和杀肿瘤活性。基于它们的结构特性,这些抗菌肽可分为三类:螺旋状肽,含有一个至几个二硫键的肽以及富含某些氨基酸(例如脯氨酸或色氨酸)的肽。这些肽大多数具有一些共同的特征,例如它们的低分子量(2-5 kDa),存在多个赖氨酸和精氨酸残基以及两亲性质。尽管尚不清楚它们杀死细菌的确切机制,但已表明导致膜渗透的肽-脂相互作用在其活性中起作用。抗生素肽的实例包括洋甘菊素,其由皮肤的皮肤分泌。非洲爪蟾 ; 人嗜中性粒细胞的防御素和人唾液中的组蛋白。天蚕素是由昆虫在感染条件下产生的。天蚕素A,B和D是紧密的同源物,由天蚕素蛾的35中发现的35-39个残基组成。
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