阿纳斯佩克/LCMV(276-286),GP276/1毫克/AS-62539
市场价:
¥1920.00
美元价:
960.00
产品分类:
其它成像系统
公司分类:
Other_imaging
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
Product Name | LCMV (276 - 286), GP276SGVENPGGYCL |
Size | 1 mg |
Catalog # | AS-62539 |
US$ | $96 |
Purity | % Peak Area By HPLC ≥ 95% |
This peptide is amino acids 276 to 286 fragment of the lymphocytic choriomeningitis virus (LCMV) glycoprotein (GP), also known as GP276. It is the H-2Db restricted epitope. LCMV has been routinely exploited for the study of adaptive immune responses to viral infection. Fifty to seventy percent of CD8 T cells at the peak of LCMV infection appear to be specific for five LCMV-derived epitopes including GP276. | |
Detailed Information | Material Safety Data Sheets (MSDS) |
Storage | -20°C |
References | Masopust, D. et al. J. Virol. 81, 2002 (2007). |
Molecular Weight | 1095.2 |
SGVENPGGYCL | |
Sequence(Three-Letter Code) | H - Ser - Gly - Val - Glu - Asn - Pro - Gly - Gly - Tyr - Cys - Leu - OH |
Product Citations | Towne, C.F. et al. (2008). Puromycin-Sensitive Aminopeptidase Limits MHC Class I Presentation in Dendritic Cells but Does Not Affect CD8 T Cell Responses during Viral Infections. J Immunol 180, 1704. |
品牌介绍
Anaspec阳离子抗菌肽是所有物种先天防御的重要组成部分。在许多生物中,包括真菌,昆虫,两栖动物和人类中,已经鉴定出100多种这些肽。这些疏水性和两亲性肽表现出抗生素,杀真菌,溶血,杀病毒和杀肿瘤活性。基于它们的结构特性,这些抗菌肽可分为三类:螺旋状肽,含有一个至几个二硫键的肽以及富含某些氨基酸(例如脯氨酸或色氨酸)的肽。这些肽大多数具有一些共同的特征,例如它们的低分子量(2-5 kDa),存在多个赖氨酸和精氨酸残基以及两亲性质。尽管尚不清楚它们杀死细菌的确切机制,但已表明导致膜渗透的肽-脂相互作用在其活性中起作用。抗生素肽的实例包括洋甘菊素,其由皮肤的皮肤分泌。非洲爪蟾 ; 人嗜中性粒细胞的防御素和人唾液中的组蛋白。天蚕素是由昆虫在感染条件下产生的。天蚕素A,B和D是紧密的同源物,由天蚕素蛾的35中发现的35-39个残基组成。
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