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当前位置: 首页 > 产品中心 > Pipette > Anaspec/Melan-A/MART-1(27-35)/1mg/AS-60608
商品详细Anaspec/Melan-A/MART-1(27-35)/1mg/AS-60608
Anaspec/Melan-A/MART-1(27-35)/1mg/AS-60608
Anaspec/Melan-A/MART-1(27-35)/1mg/AS-60608
商品编号: AS-60608
品牌: Anaspec
市场价: ¥2360.00
美元价: 1180.00
产地: 美国(厂家直采)
公司:
产品分类: 移液
公司分类: Pipette
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
DescriptionSequence(One-Letter Code)
Product NameMelan - A/MART - 1 (27 - 35)AAGIGILTV
Size1 mg
Catalog #AS-60608
US$$118
Purity% Peak Area By HPLC ≥ 95%

Melan-A is a melanocyte differentiation antigen recognized by cytotoxic T lymphocytes. This sequence is a naturally presented Melan-A/MART-1 nonamer peptide. The Melan-A/MART-1 gene is expressed by normal melanocytes, as well as by most fresh melanoma samples and melanoma cell lines. This peptide appears to be a very common immunogenic epitope for HLA-A2-restricted melanoma-specific tumor-infiltrating lymphocytes (TIL) and may be useful for the development of immunotherapeutic strategies.

Detailed InformationMaterial Safety Data Sheets (MSDS)
Storage-20°C
ReferencesRef: Kawakami, Y. et al. J. Exp. Med 180, 347 (1994); Schneider, J. et al. Int. J. Cancer 75, 451 (1998).
Molecular Weight814.6
AAGIGILTV
Sequence(Three-Letter Code)H - Ala - Ala - Gly - Ile - Gly - Ile - Leu - Thr - Val - OH
品牌介绍
Anaspec阳离子抗菌肽是所有物种先天防御的重要组成部分。在许多生物中,包括真菌,昆虫,两栖动物和人类中,已经鉴定出100多种这些肽。这些疏水性和两亲性肽表现出抗生素,杀真菌,溶血,杀病毒和杀肿瘤活性。基于它们的结构特性,这些抗菌肽可分为三类:螺旋状肽,含有一个至几个二硫键的肽以及富含某些氨基酸(例如脯氨酸或色氨酸)的肽。这些肽大多数具有一些共同的特征,例如它们的低分子量(2-5 kDa),存在多个赖氨酸和精氨酸残基以及两亲性质。尽管尚不清楚它们杀死细菌的确切机制,但已表明导致膜渗透的肽-脂相互作用在其活性中起作用。抗生素肽的实例包括洋甘菊素,其由皮肤的皮肤分泌。非洲爪蟾 ; 人嗜中性粒细胞的防御素和人唾液中的组蛋白。天蚕素是由昆虫在感染条件下产生的。天蚕素A,B和D是紧密的同源物,由天蚕素蛾的35中发现的35-39个残基组成。