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Anaspec/Luteinizing Hormone - Releasing Hormone (LH - RH), human/25 mg/AS-20782
Anaspec/Luteinizing Hormone - Releasing Hormone (LH - RH), human/25 mg/AS-20782
市场价:
¥3400.00
美元价:
1700.00
产品分类:
微球
公司分类:
Microspheres
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
Product Name | Luteinizing Hormone - Releasing Hormone (LH - RH), humanPyr - HWSYGLRPG - NH2 |
Size | 25 mg |
Catalog # | AS-20782 |
US$ | $170 |
Purity | % Peak Area By HPLC ≥ 95% |
This decapeptide is a hypothalamic hormone that controls the release of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) in the pituitary gland and promotes mating behavior. It stimulates the secretion of gonadotropins after its interaction with specific G-protein-coupled receptors that are present in plasma membranes of pituitary gonadotrophs. In addition to hypophysiotropic effect, it also plays a autocrine/paracrine role in peripheral organs such as prostate, breast and ovary. Luteinizing hormone-releasing hormone is not only a neurohormone but may also function as a neurotransmitter or neuromodulator. | |
Detailed Information | Material Safety Data Sheets (MSDS) |
Storage | -20°C |
References | Kiss, J. and B. Halasz, Neurosci 14, 69 (1985); Zheng, L. et al. Neurosci 46, 407 (1992); Collado, B. et al. Intl J Oncol 24, 725 (2004); Hoffman, G. et al. Brain Res 2005 Aug 5; [Epub ahead of print]; Wang, V. et al. Am J Obstet Gynecol 160, 984 (1989). |
Molecular Weight | 1182.3 |
Pyr-HWSYGLRPG-NH2 | |
Sequence(Three-Letter Code) | Pyr - His - Trp - Ser - Tyr - Gly - Leu - Arg - Pro - Gly - NH2 |
Product Citations | Xu, Y. et al. (2010). Porous Polymer Monolithic Column with Surface-Bound Gold Nanoparticles for the Capture and Separation of Cysteine-Containing Peptides. Anal Chem 82, 3352. |
品牌介绍
Anaspec阳离子抗菌肽是所有物种先天防御的重要组成部分。在许多生物中,包括真菌,昆虫,两栖动物和人类中,已经鉴定出100多种这些肽。这些疏水性和两亲性肽表现出抗生素,杀真菌,溶血,杀病毒和杀肿瘤活性。基于它们的结构特性,这些抗菌肽可分为三类:螺旋状肽,含有一个至几个二硫键的肽以及富含某些氨基酸(例如脯氨酸或色氨酸)的肽。这些肽大多数具有一些共同的特征,例如它们的低分子量(2-5 kDa),存在多个赖氨酸和精氨酸残基以及两亲性质。尽管尚不清楚它们杀死细菌的确切机制,但已表明导致膜渗透的肽-脂相互作用在其活性中起作用。抗生素肽的实例包括洋甘菊素,其由皮肤的皮肤分泌。非洲爪蟾 ; 人嗜中性粒细胞的防御素和人唾液中的组蛋白。天蚕素是由昆虫在感染条件下产生的。天蚕素A,B和D是紧密的同源物,由天蚕素蛾的35中发现的35-39个残基组成。
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