Anaspec/胃泌素-1，大鼠/1mg/AS-20752
市场价：
¥2620.00
美元价：
1310.00
产品分类：
信号通路
公司分类：
Signal_pathway
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| Product Name | Gastrin - 1, ratPyr - RPPMEEEEEAYGWMDF - NH2 |
| Size | 1 mg |
| Catalog # | AS-20752 |
| US$ | $131 |
| Purity | % Peak Area By HPLC ≥ 95% |
Like human Gastrin-1 Little Gastrin, rat Gastrin-1 Little Gastrin contains 17 amino acids, but differs from human Gastrin by 3 amino acids at the C-terminus. Secretion of Gastrin is induced by food intake and causes the release of gastric acid. Synthesized by the G cells in the gastric mucosa, it is one of the major bioactive forms of Gastrin (the other bioactive form is Gastrin-34). Both Gastrin-17 and Gastrin-34 are carboxy-amidated and partially tyrosine sulfated. Binding of Gastrin to the CCK2/gastrin receptor requires carboxy-amidation, however sulfation is not necessary for binding to the receptor. | |
| Detailed Information |  Material Safety Data Sheets (MSDS) |
| Storage | -20°C |
| References | Reeve, JR. et al. Peptides 2, 453 (1981)Schaffer, MH. et al. Peptides 3, 693 (1982), doi: 10.1016/0196-9781(82)90172-3Niederle, B. Wien Klin Wochenschr 119, 561 (2007), doi: 10.1007/s00508-007-0897-x.OConnor A. et. al. Digestive Dis 32, 186 (2014), doi: 10.1159/000357848Dockray, G. et.al. Pflügers Archiv 449,344 (2005)Bundgaard, JR. et al. J Biol Chem 272, 21700 (1997), doi: 10.1074/jbc.272.35.21700Yakabi, K. et al. World J Gastroenterol 14, 6334 (2008), doi: 10.3748/wjg.14.6334 |
| Molecular Weight | 2126.3 |
| Pyr-RPPMEEEEEAYGWMDF-NH2 | |
| Sequence(Three-Letter Code) | Pyr - Arg - Pro - Pro - Met - Glu - Glu - Glu - Glu - Glu - Ala - Tyr - Gly - Trp - Met - Asp - Phe - NH2 |
品牌介绍
Anaspec阳离子抗菌肽是所有物种先天防御的重要组成部分。在许多生物中，包括真菌，昆虫，两栖动物和人类中，已经鉴定出100多种这些肽。这些疏水性和两亲性肽表现出抗生素，杀真菌，溶血，杀病毒和杀肿瘤活性。基于它们的结构特性，这些抗菌肽可分为三类：螺旋状肽，含有一个至几个二硫键的肽以及富含某些氨基酸（例如脯氨酸或色氨酸）的肽。这些肽大多数具有一些共同的特征，例如它们的低分子量（2-5 kDa），存在多个赖氨酸和精氨酸残基以及两亲性质。尽管尚不清楚它们杀死细菌的确切机制，但已表明导致膜渗透的肽-脂相互作用在其活性中起作用。抗生素肽的实例包括洋甘菊素，其由皮肤的皮肤分泌。非洲爪蟾 ; 人嗜中性粒细胞的防御素和人唾液中的组蛋白。天蚕素是由昆虫在感染条件下产生的。天蚕素A，B和D是紧密的同源物，由天蚕素蛾的35中发现的35-39个残基组成。
联络我们
