Anaspec/β-淀粉样蛋白(1-42),FAM标记,人/0.1mg/AS-23526-01
商品编号:
AS-23526-01
品牌:
Anaspec
市场价:
¥3460.00
美元价:
1730.00
产品分类:
免疫组化试剂盒
公司分类:
Immunostain_SP_Kit
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
Product Name | Beta - Amyloid (1 - 42), FAM - labeled, HumanFAM - DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA |
Size | 0.1 mg |
Catalog # | AS-23526-01 |
US$ | $173 |
Purity | % Peak Area By HPLC ≥ 95% |
This is a fluorescent (FAM)-labeled ß-Amyloid peptide, Abs/Em=494/521 nm. | |
Detailed Information | DatasheetMaterial Safety Data Sheets (MSDS) |
Storage | -20°C |
References | Ref: Wei, H. et al. J. Pharmacol. 392, 117 (2000). |
Molecular Weight | 4873.4 |
FAM-DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA | |
Sequence(Three-Letter Code) | FAM - Asp - Ala - Glu - Phe - Arg - His - Asp - Ser - Gly - Tyr - Glu - Val - His - His - Gln - Lys - Leu - Val - Phe - Phe - Ala - Glu - Asp - Val - Gly - Ser - Asn - Lys - Gly - Ala - Ile - Ile - Gly - Leu - Met - Val - Gly - Gly - Val - Val - Ile - Ala - OH |
Product Citations | Fleisher-Berkovich, S. et al. (2010). Distinct modulation of microglial amyloid β phagocytosis and migration by neuropeptides. J Neuroinflammation 7, 61. doi: 10.1186/1742-2094-7-61Choucair, A. et al. (2007). Preferential accumulation of Aβ(1-42) on gel phase domains of lipid bilayers: An AFM and fluorescence study. Biochim Biophys Acta-Biomembranes 1768, 146.Saavedra, L. et al. (2007). Internalization of β-amyloid peptide by primary neurons in the absence of apolipoprotein E. J Biol Chem 282, 35722.LeVine III, H. (2004). Alzheimer"s β-peptide oligomer formation at physiologic concentrations. Anal Biochem 335, 81. |
品牌介绍
Anaspec阳离子抗菌肽是所有物种先天防御的重要组成部分。在许多生物中,包括真菌,昆虫,两栖动物和人类中,已经鉴定出100多种这些肽。这些疏水性和两亲性肽表现出抗生素,杀真菌,溶血,杀病毒和杀肿瘤活性。基于它们的结构特性,这些抗菌肽可分为三类:螺旋状肽,含有一个至几个二硫键的肽以及富含某些氨基酸(例如脯氨酸或色氨酸)的肽。这些肽大多数具有一些共同的特征,例如它们的低分子量(2-5 kDa),存在多个赖氨酸和精氨酸残基以及两亲性质。尽管尚不清楚它们杀死细菌的确切机制,但已表明导致膜渗透的肽-脂相互作用在其活性中起作用。抗生素肽的实例包括洋甘菊素,其由皮肤的皮肤分泌。非洲爪蟾 ; 人嗜中性粒细胞的防御素和人唾液中的组蛋白。天蚕素是由昆虫在感染条件下产生的。天蚕素A,B和D是紧密的同源物,由天蚕素蛾的35中发现的35-39个残基组成。
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