4000-520-616
欢迎来到免疫在线!(蚂蚁淘生物旗下平台)  请登录 |  免费注册 |  询价篮
主营:原厂直采,平行进口,授权代理(蚂蚁淘为您服务)
咨询热线电话
4000-520-616
当前位置: 首页 > 产品中心 > Tag_antibody > Anaspec/GRGDSP/5 mg/AS-22946
商品详细Anaspec/GRGDSP/5 mg/AS-22946
Anaspec/GRGDSP/5 mg/AS-22946
Anaspec/GRGDSP/5 mg/AS-22946
商品编号: AS-22946
品牌: Anaspec
市场价: ¥2040.00
美元价: 1020.00
产地: 美国(厂家直采)
公司:
产品分类: 标签抗体
公司分类: Tag_antibody
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
DescriptionSequence(One-Letter Code)
Product NameGRGDSPGRGDSP
Size5 mg
Catalog #AS-22946
US$$102
Purity% Peak Area By HPLC ≥ 95%

An inhibitor of cell attachment to salmosin and vitronectin.

Detailed InformationDatasheet
Material Safety Data Sheets (MSDS)
Storage-20°C
ReferencesRef: Kang, I-C. et al. Cancer Res. 59, 3754 (1999).
Molecular Weight587.6
GRGDSP
Sequence(Three-Letter Code)H - Gly - Arg - Gly - Asp - Ser - Pro - OH
Product CitationsLaughlin, T. et al. (2017). Development of pre-implantation porcine blastocysts cultured within alginate hydrogel systems either supplemented with secreted phosphoprotein 1 or conjugated with Arg-Gly-Asp Peptide.REPROD FERT DEV 29(12) 2345-2356.doi.org/10.1071/RD16366 Xia, P. et al. (2017).TGF-β1-induced chondrogenesis of bone marrow mesenchymal stem cells is promoted by low-intensity pulsed ultrasound through the integrin-mTOR signaling pathway.STEM CELL RES THER 8:281.doi.org/10.1186/s13287-017-0733-9Tanaka, K. et al. (2016).Branched-chain amino acids regulate insulin-like growth factor-binding protein 1 (IGFBP1) production by decidua and influence trophoblast migration through IGFBP1. MoleHu 22, 8, 890-899.https://doi.org/10.1093/molehr/gaw032Peyton, SR. et al. (2011). Marrow‐derived stem cell motility in 3D synthetic scaffold is governed by geometry along with adhesivity and stiffness. 10.1002/bit.23027.Zhou, Y. et al. (2010). Thy-1-integrin alphavbeta5 interactions inhibit lung fibroblast contraction-induced latent TGF-beta1 activation and myofibroblast differentiation. J Biol Chem 10.1074/jbc.M110.126227.Bunch, T. (2009). Integrin αIIbβ3 Activation in Chinese Hamster Ovary Cells and Platelets Increases Clustering Rather than Affinity. J Biol Chem 285, 1841.Fukushima, Y. et al. (2007). Induction of glioma cell migration by vitronectin in human serum and cerebrospinal fluid. J Neurosurg 107, 3.Jiang, H. et al. (2005). Cell-matrix entanglement and mechanical anchorage of fibroblasts in three-dimensional collagen matrices. Mol Biol Cell 16, 5070.Kvansakul, M. et al. (2004). Structure of a thrombospondin C-terminal fragment reveals a novel calcium core in the type 3 repeats. EMBO J 23, 1223.
品牌介绍
Anaspec阳离子抗菌肽是所有物种先天防御的重要组成部分。在许多生物中,包括真菌,昆虫,两栖动物和人类中,已经鉴定出100多种这些肽。这些疏水性和两亲性肽表现出抗生素,杀真菌,溶血,杀病毒和杀肿瘤活性。基于它们的结构特性,这些抗菌肽可分为三类:螺旋状肽,含有一个至几个二硫键的肽以及富含某些氨基酸(例如脯氨酸或色氨酸)的肽。这些肽大多数具有一些共同的特征,例如它们的低分子量(2-5 kDa),存在多个赖氨酸和精氨酸残基以及两亲性质。尽管尚不清楚它们杀死细菌的确切机制,但已表明导致膜渗透的肽-脂相互作用在其活性中起作用。抗生素肽的实例包括洋甘菊素,其由皮肤的皮肤分泌。非洲爪蟾 ; 人嗜中性粒细胞的防御素和人唾液中的组蛋白。天蚕素是由昆虫在感染条件下产生的。天蚕素A,B和D是紧密的同源物,由天蚕素蛾的35中发现的35-39个残基组成。