阿纳斯佩克/GRGDSP/1毫克/AS-22945
市场价：
¥460.00
美元价：
230.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| Product Name | GRGDSPGRGDSP |
| Size | 1 mg |
| Catalog # | AS-22945 |
| US$ | $23 |
| Purity | % Peak Area By HPLC ≥ 95% |
An inhibitor of cell attachment to salmosin and vitronectin. | |
| Detailed Information |  Datasheet Material Safety Data Sheets (MSDS) |
| Storage | -20°C |
| References | Kang, I-C. et al. Cancer Res. 59, 3754 (1999). |
| Molecular Weight | 587.6 |
| GRGDSP | |
| Sequence(Three-Letter Code) | H - Gly - Arg - Gly - Asp - Ser - Pro - OH |
| Product Citations | Laughlin, T. et al. (2017). Development of pre-implantation porcine blastocysts cultured within alginate hydrogel systems either supplemented with secreted phosphoprotein 1 or conjugated with Arg-Gly-Asp Peptide.REPROD FERT DEV 29(12) 2345-2356.doi.org/10.1071/RD16366 Xia, P. et al. (2017).TGF-β1-induced chondrogenesis of bone marrow mesenchymal stem cells is promoted by low-intensity pulsed ultrasound through the integrin-mTOR signaling pathway.STEM CELL RES THER 8:281.doi.org/10.1186/s13287-017-0733-9Tanaka, K. et al. (2016).Branched-chain amino acids regulate insulin-like growth factor-binding protein 1 (IGFBP1) production by decidua and influence trophoblast migration through IGFBP1. MoleHu 22, 8, 890-899.https://doi.org/10.1093/molehr/gaw032Peyton, SR. et al. (2011). Marrow‐derived stem cell motility in 3D synthetic scaffold is governed by geometry along with adhesivity and stiffness. 10.1002/bit.23027.Zhou, Y. et al. (2010). Thy-1-integrin alphavbeta5 interactions inhibit lung fibroblast contraction-induced latent TGF-beta1 activation and myofibroblast differentiation. J Biol Chem 10.1074/jbc.M110.126227.Bunch, T. (2009). Integrin αIIbβ3 Activation in Chinese Hamster Ovary Cells and Platelets Increases Clustering Rather than Affinity. J Biol Chem 285, 1841. doi: 10.1074/jbc.M109.057349Fukushima, Y. et al. (2007). Induction of glioma cell migration by vitronectin in human serum and cerebrospinal fluid. J Neurosurg 107, 3. DOI: https://doi.org/10.3171/JNS-07/09/0578Jiang, H. et al. (2005). Cell-matrix entanglement and mechanical anchorage of fibroblasts in three-dimensional collagen matrices. Mol Biol Cell 16, 5070.doi: 10.1091/mbc.E05-01-0007Kvansakul, M. et al. (2004). Structure of a thrombospondin C-terminal fragment reveals a novel calcium core in the type 3 repeats. EMBO J 23, 1223.doi: 10.1038/sj.emboj.7600166 |
品牌介绍
Anaspec阳离子抗菌肽是所有物种先天防御的重要组成部分。在许多生物中，包括真菌，昆虫，两栖动物和人类中，已经鉴定出100多种这些肽。这些疏水性和两亲性肽表现出抗生素，杀真菌，溶血，杀病毒和杀肿瘤活性。基于它们的结构特性，这些抗菌肽可分为三类：螺旋状肽，含有一个至几个二硫键的肽以及富含某些氨基酸（例如脯氨酸或色氨酸）的肽。这些肽大多数具有一些共同的特征，例如它们的低分子量（2-5 kDa），存在多个赖氨酸和精氨酸残基以及两亲性质。尽管尚不清楚它们杀死细菌的确切机制，但已表明导致膜渗透的肽-脂相互作用在其活性中起作用。抗生素肽的实例包括洋甘菊素，其由皮肤的皮肤分泌。非洲爪蟾 ; 人嗜中性粒细胞的防御素和人唾液中的组蛋白。天蚕素是由昆虫在感染条件下产生的。天蚕素A，B和D是紧密的同源物，由天蚕素蛾的35中发现的35-39个残基组成。
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