Anaspec/CEF对照肽池/1 mg/AS-61036-003
商品编号：
AS-61036-003
品牌：
Anaspec
市场价：
¥2420.00
美元价：
1210.00
产品分类：
漩涡震荡仪
公司分类：
Vortex_oscillator
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| Product Name | CEF Control Peptide Pool |
| Size | 1 mg |
| Catalog # | AS-61036-003 |
| US$ | $121 |
This product contains 0.03 mg (net) of the 32 CEF peptides for a total of 1 mg in one vial. Used in the stimulation of IFNγ release from CD8+ T cells in individuals with defined HLA types, these epitopes are useful in applications such as ELISPOT, intracellular cytokine and CTL assays. | |
| Detailed Information |  Datasheet Material Safety Data Sheets (MSDS) |
| Storage | -20°C |
| References | Ref: NIH AIDS Research and Reference Reagent Program; Currier, JR. et al. J. Immunol. Methods 260, 157 (2002); Mwau, M. et al. AIDS REs. Hum. Retroviruses 18, 611 (2002). |
| Product Citations | Mehrotra, S. et al. (2017). Vaccination with poly(IC:LC) and peptide-pulsed autologous dendritic cells in patients with pancreatic cancer. J Hematol Oncol. 10(1):82. doi: 10.1186/s13045-017-0459-2.Bhattarai, N et al. (2017). Hepatitis C virus infection inhibits a Src-kinase regulatory phosphatase and reduces T cell activation in vivo. PLoS Pathog 13(2):e1006232. doi: 10.1371/journal.ppat.1006232. eCollection 2017 Feb.Hughes, SM. (2016). Cryopreservation of Human Mucosal Leukocytes. PLoS One.11(5):e0156293. doi: 10.1371/journal.pone.0156293.Upreti, D. (2016). Change in CD3ζ-chain expression is an independent predictor of disease status in head and neck cancer patients. Int J Cancer. 139(1):122-9. doi: 10.1002/ijc.30046.Chiu, YL. et al. (2014). Sprouty-2 regulates HIV-specific T cell polyfunctionality. J Clin Invest 124, 198. doi: 10.1172/JC170510.Richmond, ME. et al.(2014). Memory phenotypes of HIV-specific CD8+ T cell responses are independent of functional activity as defined by cytokine output. Open J Immunol 4, 83. doi: 10.4236/oji.2014.43012.Sedegah, M. et al. (2014). Sterile immunity to malaria after DNA prime/adenovirus boost immunization is associated with effector memory CD8+ T cells targeting AMA1 class I epitopes. PloS one 9, e106241. doi: 10.1371/journal.pone.0106241.Sehgal, K. et al. (2014). Nanoparticle-mediated combinatorial targeting of multiple human dendritic cell (DC) subsets leads to enhanced T cell activation via IL-15dependent DC crosstalk. J Immunol 193, 2297. doi: 10.4049/jimmunol.1400489.Wick, DA. et al. (2014). Surveillance of the tumor mutanome by T cells during progression from primary to recurrent ovarian cancer. Clin Cancer Res 20, 1125.Cecil, DL. et al. (2013). T-helper I immunity, specific for the breast cancer antigen insulin-like growth factor-I receptor (IGF-IR), is associated with increased adiposity. Breast Cancer Res Treatment 139, 657.Dhodapkar, KM. et al. (2013). SOX2-specific adaptive immunity and response to immunotherapy in non-small cell lung cancer. Oncoimmunol 2, e25205. doi: 10.4161/onci.25205.Eypper, EH. et al. (2013). Transcutaneous immunization of healthy volunteers with an attenuated Listeria monocytogenes vaccine strain and cholera toxin adjuvant. Vaccine 31, 3257.Sedegah, M. et al. (2013). Identification of minimal human MHC-restricted CD8+ T-cell epitopes within the Plasmodium falciparum circumsporozoite protein (CSP). Malaria J 12, 185.Bayard, F. et al. (2012). T-cell responses to hepatitis B splice-generated protein of hepatitis B virus and inflammatory cytokines/chemokines in chronic hepatitis B patients. ANRS study: HB EP 02 HBSP-FIBRO. J Viral Hepatitis 19, 872. doi: 10.1111/j.1365-2893.2012.01611.x.Fairman, P. & JB. Angel (2012). The effect of human immunodeficiency virus-1 on monocyte-derived dendritic cell maturation and function. Clin Exp Immunol 170, 101. doi: 10.1111/j.1365-2249.2012.04628.x.Habersetzer, F. et al. (2011). A Poxvirus vaccine is safe, induces T-Cell responses, and decreases viral load in patients with chronic Hepatitis C. Gastroenterol 141, 890. http://www.sciencedirect.com/science/article/pii/S0016508511007669Matijevic, M. et al. (2011). Immunization with a poly (lactide co-glycolide) encapsulated plasmid DNA expressing antigenic regions of HPV 16 and 18 results in an increase in the precursor frequency of T cells that respond to epitopes from HPV 16, 18, 6 and 11. Cellular Immunol 270, 62.Olson, WC. et al. (2011). Shipping blood to a central laboratory in multicenter clinical trials: effect of ambient temperature on specimen temperature, and effects of temperature on mononuclear cell yield, viability and immunologic function.J Transl Med 9. 26. doi: 10.1186/1479-5876-9-26. Richmond, M. et al. (2011). Epitope mapping of HIV-specific CD8+ T cell responses by multiple immunological readouts reveals distinct specificities defined by function. J Virol 85, 1275. doi: 10.1128/JVI.01707-10.Nielsen, JS. et al. (2010). An in vitro-transcribed-mRNA polyepitope construct encoding 32 distinct HLA class I-restricted epitopes from CMV, EBV, and Influenza for use as a functional control in human immune monitoring studies. J Immunol Methods 360, 149.Boaz, M. et al. (2008). Measuring T-cell immunity in HIV vaccine clinical trials: PBMC and ELISPOT assay proficiency concordance in laboratories from 3 continents. Clin Vaccine Immunol doi:10.1128/CVI.00326-08.Jones, RB. et al. (2008). Tim-3 expression defines a novel population of dysfunctional T cells with highly elevated frequencies in progressive HIV-1 infection. J Exp Med 205, 2763. doi: 10.1084/jem.20081398.Bull, M. et al. (2007). Defining blood processing parameters for optimal detection of cryopreserved antigen-specific responses for HIV vaccine trials. J Immunol Methods 322, 57.Moodie, Z. et al. (2006). Statistical positivity criteria for the analysis of ELISpot assay data in HIV-1 vaccine trials. J Immunol Methods 315, 121. |
品牌介绍
Anaspec阳离子抗菌肽是所有物种先天防御的重要组成部分。在许多生物中，包括真菌，昆虫，两栖动物和人类中，已经鉴定出100多种这些肽。这些疏水性和两亲性肽表现出抗生素，杀真菌，溶血，杀病毒和杀肿瘤活性。基于它们的结构特性，这些抗菌肽可分为三类：螺旋状肽，含有一个至几个二硫键的肽以及富含某些氨基酸（例如脯氨酸或色氨酸）的肽。这些肽大多数具有一些共同的特征，例如它们的低分子量（2-5 kDa），存在多个赖氨酸和精氨酸残基以及两亲性质。尽管尚不清楚它们杀死细菌的确切机制，但已表明导致膜渗透的肽-脂相互作用在其活性中起作用。抗生素肽的实例包括洋甘菊素，其由皮肤的皮肤分泌。非洲爪蟾 ; 人嗜中性粒细胞的防御素和人唾液中的组蛋白。天蚕素是由昆虫在感染条件下产生的。天蚕素A，B和D是紧密的同源物，由天蚕素蛾的35中发现的35-39个残基组成。
联络我们
