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Anaspec/Spexin - 2 (53 - 70), amidated, human/mouse/rat/1 mg/AS-65570
Anaspec/Spexin - 2 (53 - 70), amidated, human/mouse/rat/1 mg/AS-65570
市场价:
¥5120.00
美元价:
2560.00
产品分类:
细胞成像系统
公司分类:
Cell_imaging_system
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
Product Name | Spexin - 2 (53 - 70), amidated, human/mouse/rat |
Size | 1 mg |
Catalog # | AS-65570 |
US$ | $256 |
Purity | Peak Area by HPLC ≥95% |
This is amidated Spexin-2 (53-70) peptide showing similar biological function as that of its non- amidated version (Cat # 65586) as a central modulator of cardiovascular and renal function. Spexin-2 is a novel peptide hormone that is derived from prohormone proNPQ and is conserved amongst mammalian species. | |
Detailed Information | DatasheetMaterial Safety Data Sheets (MSDS) |
Storage | This peptide is shipped at ambient temperature. Upon receipt, store lyophilized peptide at 20°C or lower. Reconstituted peptide can be aliquoted and stored at 20°C or lower. |
References | 1.Gu L. et al. Peptides 71, 232-239 (2015). |
Molecular Weight | 2158.9 |
FISDQSRRKDLSDRPLPE-NH2 | |
Sequence(Three-Letter Code) | Phe - Ile - Ser - Asp - Gln - Ser - Arg - Arg - Lys - Asp - Leu - Ser - Asp - Arg - Pro - Leu - Pro - Glu - NH2 |
品牌介绍
Anaspec阳离子抗菌肽是所有物种先天防御的重要组成部分。在许多生物中,包括真菌,昆虫,两栖动物和人类中,已经鉴定出100多种这些肽。这些疏水性和两亲性肽表现出抗生素,杀真菌,溶血,杀病毒和杀肿瘤活性。基于它们的结构特性,这些抗菌肽可分为三类:螺旋状肽,含有一个至几个二硫键的肽以及富含某些氨基酸(例如脯氨酸或色氨酸)的肽。这些肽大多数具有一些共同的特征,例如它们的低分子量(2-5 kDa),存在多个赖氨酸和精氨酸残基以及两亲性质。尽管尚不清楚它们杀死细菌的确切机制,但已表明导致膜渗透的肽-脂相互作用在其活性中起作用。抗生素肽的实例包括洋甘菊素,其由皮肤的皮肤分泌。非洲爪蟾 ; 人嗜中性粒细胞的防御素和人唾液中的组蛋白。天蚕素是由昆虫在感染条件下产生的。天蚕素A,B和D是紧密的同源物,由天蚕素蛾的35中发现的35-39个残基组成。
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