Anaspec/Spexin（36-49），酰胺化，人/小鼠/大鼠/1 mg/AS-65569
市场价：
¥2580.00
美元价：
1290.00
产品分类：
其它检测试剂盒
公司分类：
Other_kits
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| Product Name | Spexin (36 - 49), amidated, human/mouse/rat |
| Size | 1 mg |
| Catalog # | AS-65569 |
| US$ | $129 |
| Purity | Peak Area by HPLC ≥95% |
Spexin is a novel peptide hormone that is derived from prohormone proNPQ and is conserved amongst mammalian species. Spexin (36-49) is post-translationally amidated with a C-terminal amidation processing signal motif (GRR) following Q49 residue of the pro-hormone. Spexin reduces adipocyte uptake of long chain fatty acids and causes weight loss in rodents. Recently it was suggested that this peptide may play a role in lipid and glucose metabolism in patients with type-2 diabetes mellitus. | |
| Detailed Information |  Datasheet Material Safety Data Sheets (MSDS) |
| Storage | This peptide is shipped at ambient temperature. Upon receipt, store lyophilized peptide at 20°C or lower. Reconstituted peptide can be aliquoted and stored at 20°C or lower. |
| References | 1.Gu L. et al. Peptides 71, 232-239 (2015). |
| Molecular Weight | 1620 |
| NWTPQAMLYLKGAQ-NH2 | |
| Sequence(Three-Letter Code) | Asn - Trp - Thr - Pro - Gln - Ala - Met - Leu - Tyr - Leu - Lys - Gly - Ala - Gln - NH2 |
品牌介绍
Anaspec阳离子抗菌肽是所有物种先天防御的重要组成部分。在许多生物中，包括真菌，昆虫，两栖动物和人类中，已经鉴定出100多种这些肽。这些疏水性和两亲性肽表现出抗生素，杀真菌，溶血，杀病毒和杀肿瘤活性。基于它们的结构特性，这些抗菌肽可分为三类：螺旋状肽，含有一个至几个二硫键的肽以及富含某些氨基酸（例如脯氨酸或色氨酸）的肽。这些肽大多数具有一些共同的特征，例如它们的低分子量（2-5 kDa），存在多个赖氨酸和精氨酸残基以及两亲性质。尽管尚不清楚它们杀死细菌的确切机制，但已表明导致膜渗透的肽-脂相互作用在其活性中起作用。抗生素肽的实例包括洋甘菊素，其由皮肤的皮肤分泌。非洲爪蟾 ; 人嗜中性粒细胞的防御素和人唾液中的组蛋白。天蚕素是由昆虫在感染条件下产生的。天蚕素A，B和D是紧密的同源物，由天蚕素蛾的35中发现的35-39个残基组成。
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