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Anaspec/FRETS - VWF73 (Fluorescence - Quenching Substrate for ADAMTS - 13)/0.1 mg/AS-63728-01
Anaspec/FRETS - VWF73 (Fluorescence - Quenching Substrate for ADAMTS - 13)/0.1 mg/AS-63728-01
商品编号:
AS-63728-01
品牌:
Anaspec
市场价:
¥6240.00
美元价:
3120.00
产品分类:
细胞成像系统
公司分类:
Cell_imaging_system
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
Product Name | FRETS - VWF73 (Fluorescence - Quenching Substrate for ADAMTS - 13)DRE - Dap(Nma) - APNLVYMVTG - Dpa(Dnp) - PASDEIKRLPGDIQVVPIGVGPNANVQELERIGWPNAPILIQDFETLPREAPDLVLQR |
Size | 0.1 mg |
Catalog # | AS-63728-01 |
US$ | $312 |
Purity | % Peak Area By HPLC ≥ 95% |
FRETS-VWF73 is a very powerful Fluorescence-Quenching Substrate for the VWF cleaving protease ADAMTS-13. It is commonly used as a useful tool for the rapid measurement of ADAMTS-13 activity in plasma and is a predictive marker for various thrombotic diseases like TPP. Our new substrate FRETS-VWF73 can be easily used with a 96-well format in commercial plate readers. | |
Detailed Information | Material Safety Data Sheets (MSDS) |
Storage | -20°C |
References | K. Kokame, et al. Br. J. Haematol., 129, 93-100 (2005) |
Molecular Weight | 8314.3 |
DRE-Dap(Nma)-APNLVYMVTG-Dap(Dnp)-PASDEIKRLPGDIQVVPIGVGPNANVQELERIGWPNAPILIQDFETLPREAPDLVLQR | |
Sequence(Three-Letter Code) | H - Asp - Arg - Glu - Dap(Nma) - Ala - Pro - Asn - Leu - Val - Tyr - Met - Val - Thr - Gly - Dap(Dnp) - Pro - Ala - Ser - Asp - Glu - Ile - Lys - Arg - Leu - Pro - Gly - Asp - Ile - Gln - Val - Val - Pro - Ile - Gly - Val - Gly - Pro - Asn - Ala - Asn - Val - Gln - Glu - Leu - Glu - Arg - Ile - Gly - Trp - Pro - Asn - Ala - Pro - Ile - Leu - Ile - Gln - Asp - Phe - Glu - Thr - Leu - Pro - Arg - Glu - Ala - Pro - Asp - Leu - Val - Leu - Gln - Arg - OH |
品牌介绍
Anaspec阳离子抗菌肽是所有物种先天防御的重要组成部分。在许多生物中,包括真菌,昆虫,两栖动物和人类中,已经鉴定出100多种这些肽。这些疏水性和两亲性肽表现出抗生素,杀真菌,溶血,杀病毒和杀肿瘤活性。基于它们的结构特性,这些抗菌肽可分为三类:螺旋状肽,含有一个至几个二硫键的肽以及富含某些氨基酸(例如脯氨酸或色氨酸)的肽。这些肽大多数具有一些共同的特征,例如它们的低分子量(2-5 kDa),存在多个赖氨酸和精氨酸残基以及两亲性质。尽管尚不清楚它们杀死细菌的确切机制,但已表明导致膜渗透的肽-脂相互作用在其活性中起作用。抗生素肽的实例包括洋甘菊素,其由皮肤的皮肤分泌。非洲爪蟾 ; 人嗜中性粒细胞的防御素和人唾液中的组蛋白。天蚕素是由昆虫在感染条件下产生的。天蚕素A,B和D是紧密的同源物,由天蚕素蛾的35中发现的35-39个残基组成。
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