Anaspec/组氨酸蛋白酶抑制剂-5/1 mg/AS-61001
市场价:
¥3980.00
美元价:
1990.00
产品分类:
克隆试剂盒
公司分类:
Cloning_kit
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
Product Name | Histatin - 5DSHAKRHHGYKRKFHEKHHSHRGY |
Size | 1 mg |
Catalog # | AS-61001 |
US$ | $199 |
Purity | % Peak Area By HPLC ≥ 95% |
Histatin 5 is a human basic salivary anti-microbial peptide with strong fungicidal properties. | |
Detailed Information | DatasheetMaterial Safety Data Sheets (MSDS) |
Storage | -20°C |
References | Ref: Helmerhorst, E. et al. J. Biol. Chem. 274, 7286 (1999). |
Molecular Weight | 3036.3 |
DSHAKRHHGYKRKFHEKHHSHRGY | |
Sequence(Three-Letter Code) | H - Asp - Ser - His - Ala - Lys - Arg - His - His - Gly - Tyr - Lys - Arg - Lys - Phe - His - Glu - Lys - His - His - Ser - His - Arg - Gly - Tyr - OH |
Product Citations | Stover, E. et al. (2013). Screening antimicrobial peptides in vitro for use in developing transgenic citrus resistant to Huanglongbing and citrus canker. J Amer Soc Hort Sci 138. 142.Swidergall, M. et al. (2013). Candida albicans mucin Msb2 Is a broad-tange protectant against antimicrobial peptides. Antimicrob Agents Chemother 57, 3917. doi: 10.1128/AAC.00862-13.Konopka, K. et al. (2010). Susceptibility of Candida biofilms to histatin 5 and fluconazole. Antonie van Leeuwenhoek 97, 413. |
品牌介绍
Anaspec阳离子抗菌肽是所有物种先天防御的重要组成部分。在许多生物中,包括真菌,昆虫,两栖动物和人类中,已经鉴定出100多种这些肽。这些疏水性和两亲性肽表现出抗生素,杀真菌,溶血,杀病毒和杀肿瘤活性。基于它们的结构特性,这些抗菌肽可分为三类:螺旋状肽,含有一个至几个二硫键的肽以及富含某些氨基酸(例如脯氨酸或色氨酸)的肽。这些肽大多数具有一些共同的特征,例如它们的低分子量(2-5 kDa),存在多个赖氨酸和精氨酸残基以及两亲性质。尽管尚不清楚它们杀死细菌的确切机制,但已表明导致膜渗透的肽-脂相互作用在其活性中起作用。抗生素肽的实例包括洋甘菊素,其由皮肤的皮肤分泌。非洲爪蟾 ; 人嗜中性粒细胞的防御素和人唾液中的组蛋白。天蚕素是由昆虫在感染条件下产生的。天蚕素A,B和D是紧密的同源物,由天蚕素蛾的35中发现的35-39个残基组成。
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