Anaspec/Apidaecin IB/1 mg/AS-62044
市场价：
¥2260.00
美元价：
1130.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| Product Name | Apidaecin IBGNNRPVYIPQPRPPHPRL |
| Size | 1 mg |
| Catalog # | AS-62044 |
| US$ | $113 |
| Purity | % Peak Area By HPLC ≥ 95% |
Apidaecin IB is an insect antimicrobial peptide showing a significant sequence homology and a common mechanism of action with drosocin, but is devoid of any pore-forming activity. Apidaecins are the most prominent components of the honey bee humoral defense against microbial invasion. | |
| Detailed Information |  Material Safety Data Sheets (MSDS) |
| Storage | -20°C |
| References | Casteels-Josson, K. et al. EMBO J. 12, 1569 (1993); Gobbo, M. et al. J. Med. Chem. 45, 4494 (2002). |
| Molecular Weight | 2108.4 |
| GNNRPVYIPQPRPPHPRL | |
| Sequence(Three-Letter Code) | H - Gly - Asn - Asn - Arg - Pro - Val - Tyr - Ile - Pro - Gln - Pro - Arg - Pro - Pro - His - Pro - Arg - Leu - OH |
| Product Citations | Yu, G. et al. (2016). Combination effects of antimicrobial peptides Antimicrob Agents Chemother doi: 10.1128/AAC02434-15.Stover, E. et al. (2013). Screening antimicrobial peptides in vitro for use in developing transgenic citrus resistant to Huanglongbing and citrus canker. J Amer Soc Hort Sci 138. 142.Zhou, Y. et al. (2011). iTRAQ-coupled 2-D LC-MS/MS analysis of membrane protein profile in Escherichia coli incubated with apidaecin IB. PLoS ONE doi:10.1371/journal.pone.0020442 |
品牌介绍
Anaspec阳离子抗菌肽是所有物种先天防御的重要组成部分。在许多生物中，包括真菌，昆虫，两栖动物和人类中，已经鉴定出100多种这些肽。这些疏水性和两亲性肽表现出抗生素，杀真菌，溶血，杀病毒和杀肿瘤活性。基于它们的结构特性，这些抗菌肽可分为三类：螺旋状肽，含有一个至几个二硫键的肽以及富含某些氨基酸（例如脯氨酸或色氨酸）的肽。这些肽大多数具有一些共同的特征，例如它们的低分子量（2-5 kDa），存在多个赖氨酸和精氨酸残基以及两亲性质。尽管尚不清楚它们杀死细菌的确切机制，但已表明导致膜渗透的肽-脂相互作用在其活性中起作用。抗生素肽的实例包括洋甘菊素，其由皮肤的皮肤分泌。非洲爪蟾 ; 人嗜中性粒细胞的防御素和人唾液中的组蛋白。天蚕素是由昆虫在感染条件下产生的。天蚕素A，B和D是紧密的同源物，由天蚕素蛾的35中发现的35-39个残基组成。
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