Anaspec/Rat Renin Inhibitor Peptide, WFML Peptide/1 mg/AS-60463-1
商品编号：
AS-60463-1
品牌：
Anaspec
市场价：
¥3720.00
美元价：
1860.00
产品分类：
细胞裂解和提取物
公司分类：
Cell_lysis
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| Product Name | Rat Renin Inhibitor Peptide, WFML PeptideAc - HPFV - (Sta) - LF - NH2 |
| Size | 1 mg |
| Catalog # | AS-60463-1 |
| US$ | $186 |
| Purity | % Peak Area By HPLC ≥ 95% |
A specific rat renin inhibitor. | |
| Detailed Information |  Material Safety Data Sheets (MSDS) |
| Storage | -20°C |
| References | Ref: Iyer, SN. et al. J. Cardiovasc. Pharmacol. 31, 464 (1998). |
| Molecular Weight | 957.3 |
| Ac-HPFV-(Sta)-LF-NH2 | |
| Sequence(Three-Letter Code) | Ac - His - Pro - Phe - Val - Sta - Leu - Phe - NH2 |
| Product Citations | Wang, F. et al. (2014). COX-2 mediates angiotensin II-induced (pro) renin receptor expression in the rat renal medulla. Am J Physiol Renal Physiol 307, F25. doi: 10.1152/ajprenal.00548.2013. Westwood, BM. & MC. Chappell (2012). Divergent pathways for the angiotensin-(112) metabolism in the rat circulation and kidney. Peptides 35, 190. doi:10.1016/j.peptides.2012.03.025.Chao, J. et al. (2011). Renin released from mast cells activated by circulating MCP-1 initiates the microvascular phase of the systemic inflammation of alveolar hypoxia. Am J Physiol Heart Circ Physiol 301, H2264. doi: 10.1152/ajpheart.00461.2011. Gonzalez, A. et al. (2011). Soluble Form of the (Pro)Renin Receptor Is Augmented in the Collecting Duct and Urine of Chronic Angiotensin IIDependent Hypertensive Rats. Hypertension 57, 859. doi: 10.1161/HYPERTENSIONAHA.110.167957.Gonzalez, A. et al. (2011). Angiotensin II stimulates Renin in inner medullary collecting duct cells via Protein Kinase C and independent of epithelial Sodium channel and mineralocorticoid receptor activity. Hypertension 57, 594. doi: 10.1161/HYPERTENSIONAHA.110.165902.Liu, L. et al. (2011). Increased renin excretion is associated with augmented urinary angiotensin II levels in chronic angiotensin II-infused hypertensive rats. Am J Physiol Renal Physiol 301, F1195. doi: 10.1152/ajprenal.00339.2011. Stodola, T. et al. (2011). Characterization of the genomic structure and function of regions influencing renin and angiogenesis in the SS rat. Physiol Genomics 43, 808. doi: 10.1152/physiolgenomics.00171.2010.Senador, D. et al. (2010). Cardiovascular interactions between losartan and fructose in mice. J Cardiovasc Pharmacol Ther 15, 68. doi: 10.1177/1074248409351409.Trask, A. et al. (2008). Angiotensin-(1-12) is an alternate substrate for angiotensin peptide production in the heart. Am J Physiol Heart Circ Physiol 294, H2242. doi: 10.1152/ajpheart.00175.2008.Ferrario, CM. et al. (2005). Effect of angiotensin-converting enzyme inhibition and angiotensin II receptor blockers on cardiac angiotensin-converting enzyme 2. Circulation 111, 2605. doi: 10.1161/CIRCULATIONAHA.104.510461.Ferrario, CM. et al. (2005). Effects of renin-angiotensin system blockade on renal angiotensin-(1-7) forming enzymes and receptors. Kidney Intl 68, 2189. doi: 10.1111/j.1523-1755.2005.00675.xNakamura, S. et al. (2003). Angiotensin receptors contribute to blood pressure homeostasis in salt-depleted SHR. Am J Physiol Regul Integr Comp Physiol 284, R164. doi: 10.1152/ajpregu.00210.2002 |
品牌介绍
Anaspec阳离子抗菌肽是所有物种先天防御的重要组成部分。在许多生物中，包括真菌，昆虫，两栖动物和人类中，已经鉴定出100多种这些肽。这些疏水性和两亲性肽表现出抗生素，杀真菌，溶血，杀病毒和杀肿瘤活性。基于它们的结构特性，这些抗菌肽可分为三类：螺旋状肽，含有一个至几个二硫键的肽以及富含某些氨基酸（例如脯氨酸或色氨酸）的肽。这些肽大多数具有一些共同的特征，例如它们的低分子量（2-5 kDa），存在多个赖氨酸和精氨酸残基以及两亲性质。尽管尚不清楚它们杀死细菌的确切机制，但已表明导致膜渗透的肽-脂相互作用在其活性中起作用。抗生素肽的实例包括洋甘菊素，其由皮肤的皮肤分泌。非洲爪蟾 ; 人嗜中性粒细胞的防御素和人唾液中的组蛋白。天蚕素是由昆虫在感染条件下产生的。天蚕素A，B和D是紧密的同源物，由天蚕素蛾的35中发现的35-39个残基组成。
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