Anaspec/侵略性和#7488ᴹ β - 淀粉样蛋白（1-42），人/0.25 mg净肽/AS-72216
市场价：
¥5420.00
美元价：
2710.00
产品分类：
数字PCR系统
公司分类：
Digital_PCR_system
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| Product Name | AggreSureᵀᴹβ - Amyloid (1 - 42), HumanDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA |
| Size | 0.25 mg NET peptide |
| Catalog # | AS-72216 |
| US$ | $271 |
| Purity | >95% |
AggreSure beta-Amyloid (1-42) peptide is pretreated and tested for aggregation using SensoLyte® ThT Aβ42 Aggregation kit (Cat# 72214). Aggregation Guaranteed! | |
| Images |  |
| Detailed Information |  Datasheet Material Safety Data Sheets (MSDS) |
| Storage | 20°C |
| Molecular Weight | 4514.1 |
| DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA | |
| Sequence(Three-Letter Code) | H - Asp - Ala - Glu - Phe - Arg - His - Asp - Ser - Gly - Tyr - Glu - Val - His - His - Gln - Lys - Leu - Val - Phe - Phe - Ala - Glu - Asp - Val - Gly - Ser - Asn - Lys - Gly - Ala - Ile - Ile - Gly - Leu - Met - Val - Gly - Gly - Val - Val - Ile - Ala - OH |
| Product Citations | Cheng, Q. et al (2018). TREM2-activating antibodies abrogate the negative pleiotropic effects of the Alzheimer"s disease variant Trem2(R47H) on murine myeloid cell function. J Biol Chem 293(32):12620-12633. doi: 10.1074/jbc.RA118.001848.Reinhardt, S. et al. (2018). Identification of disulfiram as a secretase-modulating compound with beneficial effects on Alzheimer"s disease hallmarks. Sci Rep 8(1):1329. doi: 10.1038/s41598-018-19577-7.Livadiotis, G. et al (2017). Experimental Analysis of Interacting HT22 Plasma Membrane Cholesterol and β-Amyloid. Advances in Alzheimer"s Disease 6(04):75.Wang, MJ. et al. (2017). Oligomeric forms of amyloid-β protein in plasma as a potential blood-based biomarker for Alzheimer"s disease. Alzheimers Res Ther 9(1):98. doi: 10.1186/s13195-017-0324-0.An, SSA. et al. (2017). Dynamic changes of oligomeric amyloid β levels in plasma induced by spiked synthetic Aβ(42). Alzheimers Res Ther 9(1):86. doi: 10.1186/s13195-017-0310-6. |
品牌介绍
Anaspec阳离子抗菌肽是所有物种先天防御的重要组成部分。在许多生物中，包括真菌，昆虫，两栖动物和人类中，已经鉴定出100多种这些肽。这些疏水性和两亲性肽表现出抗生素，杀真菌，溶血，杀病毒和杀肿瘤活性。基于它们的结构特性，这些抗菌肽可分为三类：螺旋状肽，含有一个至几个二硫键的肽以及富含某些氨基酸（例如脯氨酸或色氨酸）的肽。这些肽大多数具有一些共同的特征，例如它们的低分子量（2-5 kDa），存在多个赖氨酸和精氨酸残基以及两亲性质。尽管尚不清楚它们杀死细菌的确切机制，但已表明导致膜渗透的肽-脂相互作用在其活性中起作用。抗生素肽的实例包括洋甘菊素，其由皮肤的皮肤分泌。非洲爪蟾 ; 人嗜中性粒细胞的防御素和人唾液中的组蛋白。天蚕素是由昆虫在感染条件下产生的。天蚕素A，B和D是紧密的同源物，由天蚕素蛾的35中发现的35-39个残基组成。
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